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BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia

Authors :
Giuseppina Bonaviri
Gary Donohoe
Michael Gill
Pietro Bria
Carlo Caltagirone
Paola Bossù
Alberto Siracusano
Ivo Alex Rubino
Francesco Angelucci
Gianfranco Spalletta
Sergio Bernardini
Giovanni Martinotti
Derek W. Morris
Ilaria Spoletini
Aiden Corvin
Source :
European psychiatry : the journal of the Association of European Psychiatrists. 25(6)
Publication Year :
2009

Abstract

Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.

Details

ISSN :
17783585
Volume :
25
Issue :
6
Database :
OpenAIRE
Journal :
European psychiatry : the journal of the Association of European Psychiatrists
Accession number :
edsair.doi.dedup.....1911d64ff08e432e5525fc5279288ba7