Uterine Artery Embolization for the Treatment of Adenomyosis: A Systematic Review and Meta-Analysis

Authors :: Marieke Smink
Paul N.M. Lohle
Caroline Wong
Jos W. R. Twisk
Wouter J. K. Hehenkamp
Judith A.F. Huirne
Linda J. Schoonmade
Annefleur M. de Bruijn
Source :: de Bruijn, A M, Smink, M, Lohle, P N M, Huirne, J A F, Twisk, J W R, Wong, C, Schoonmade, L & Hehenkamp, W J K 2017, ' Uterine Artery Embolization for the Treatment of Adenomyosis : A Systematic Review and Meta-Analysis ', Journal of Vascular and Interventional Radiology, vol. 28, no. 12 . https://doi.org/10.1016/j.jvir.2017.07.034
Publication Year :: 2017
Publisher :: Elsevier BV, 2017.
Abstract: The effect of uterine artery embolization (UAE) on symptomatic adenomyosis was evaluated in a systematic review and meta-analysis. Four groups were evaluated: short-term (< 12 months) pure adenomyosis, short-term adenomyosis with fibroids (combined adenomyosis), long-term (> 12 months) pure adenomyosis, and long-term combined adenomyosis. Improvement of symptoms occurred in 83.1% (872/1,049) of patients. Reported symptom reduction was 4.8% greater in the short-term combined group (P = .169) and 11.4% greater in the long-term combined group (P = .003). Uterine volume was reduced in all patients at 3 months. The effects of UAE on symptom improvement and uterine volume reduction in patients with adenomyosis are encouraging.

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