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Recurrence of Genital Infections With 9 Human Papillomavirus (HPV) Vaccine Types (6, 11, 16, 18, 31, 33, 45, 52, and 58) Among Men in the HPV Infection in Men (HIM) Study
- Source :
- Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual), Universidade de São Paulo (USP), instacron:USP
- Publication Year :
- 2018
- Publisher :
- Oxford University Press (OUP), 2018.
-
Abstract
- Background The purpose of this study was to assess genital recurrence of human papillomavirus (HPV) genotypes included in the 9-valent vaccine and to investigate factors associated with recurrence among men in the HPV Infection in Men (HIM) Study. Methods Men were followed every 6 months for a median of 3.7 years. HPV genotypes were detected using Roche linear array. Factors associated with type-specific HPV recurrence (infections occurring after a ≥12-month infection-free period) were assessed. Results In type-specific analyses, 31% of prior prevalent and 20% of prior incident infections recurred. Among prevalent infections, HPV types 52, 45, 16, 58, and 6 and among incident infections, HPV types 58, 52, 18, 16, and 11 had the highest rates of recurrence. New sexual partners (male or female) and frequency of sexual intercourse with female partners were associated with HPV-6, -16, -31, and -58 infection recurrence. In grouped analyses, lifetime and new male sexual partners were associated with recurrence of prior incident infection with any of the 9 HPV types. Conclusions Recurrence of genital HPV infections is relatively common among men and associated with high-risk sexual behavior. Further studies are needed to understand the role of HPV recurrence in the etiology of HPV-associated diseases.
- Subjects :
- Male
0301 basic medicine
medicine.medical_specialty
Genotype
Sexual Behavior
Major Articles and Brief Reports
03 medical and health sciences
Risk-Taking
0302 clinical medicine
Recurrence
Internal medicine
medicine
Humans
Immunology and Allergy
Sex organ
Human papillomavirus
Mexico
Papillomaviridae
business.industry
Viral Vaccine
Papillomavirus Infections
HPV infection
virus diseases
Viral Vaccines
Sexually Transmitted Diseases, Viral
MULHERES
medicine.disease
Sexual intercourse
030104 developmental biology
Infectious Diseases
Sexual behavior
030220 oncology & carcinogenesis
DNA, Viral
Florida
Etiology
Female
business
Brazil
Subjects
Details
- ISSN :
- 15376613 and 00221899
- Volume :
- 218
- Database :
- OpenAIRE
- Journal :
- The Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....18a06733c78decea1ca1deb84f546f88