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Hypoparathyroidism: An Uncommon Complication Associated With Immune Checkpoint Inhibitor Therapy
- Source :
- Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 4, Iss 6, Pp 821-825 (2020)
- Publication Year :
- 2020
- Publisher :
- Elsevier, 2020.
-
Abstract
- As immune checkpoint inhibitor drugs are being used in the treatment of some cancers, unusual adverse events are being reported, labeled as immune-related adverse events. Various endocrinopathies related to immune-related adverse events have been described, among which hypoparathyroidism is exceedingly rare. We report a case of hypoparathyroidism induced by immune checkpoint drugs, highlighting the need for awareness of this emerging complication.
- Subjects :
- Immune checkpoint inhibitors
animal diseases
ICI, immune checkpoint inhibitor
Parathyroid hormone
chemical and pharmacologic phenomena
Case Report
030204 cardiovascular system & hematology
Bioinformatics
PD-1, programmed cell death protein 1
03 medical and health sciences
0302 clinical medicine
Programmed cell death 1
Medicine
030212 general & internal medicine
PTH, parathyroid hormone
Adverse effect
lcsh:R5-920
biology
business.industry
biochemical phenomena, metabolism, and nutrition
medicine.disease
Immune checkpoint
Hypoparathyroidism
biology.protein
bacteria
CaSR, calcium-sensing receptor
Calcium-sensing receptor
lcsh:Medicine (General)
business
Complication
irAE, immune-related adverse event
Subjects
Details
- Language :
- English
- ISSN :
- 25424548
- Volume :
- 4
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Mayo Clinic Proceedings: Innovations, Quality & Outcomes
- Accession number :
- edsair.doi.dedup.....18846d72bc2ff397a40731172ea744a7