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Behind the Scene: Surprises and Snags of Pseudogenes
- Source :
- Critical Reviews in Eukaryotic Gene Expression. 31:67-78
- Publication Year :
- 2021
- Publisher :
- Begell House, 2021.
-
Abstract
- The junk DNA "pseudogenes," known as genomic fossils, are characterized by their ubiquitousness and abundance within the genomic structure. These genomics sets are recognized by the potential activity of meta-regulating the parent genes; these are transcribed into interfering RNA, consequently acting on miRNA concentration, thereby shedding light on the crosstalk of the pseudogenes' miRNA, siRNA, lncRNA/tumor therapy co-relationship. Moreover, an upcoming visualization regarding pseudogenes is under investigation, which describes the potentiality of pseudogenes as a fundamental component of cancerous evolutionary processing tools. Accordingly, here is a systematic review covering pseudobirth, pseudosignatures, and functional properties of pseudogenes, concluding that these pseudogenes are hypothetically predictive tumor therapies.
Details
- ISSN :
- 10454403
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Critical Reviews in Eukaryotic Gene Expression
- Accession number :
- edsair.doi.dedup.....182cf31a3ce725f649447efba1bcd8c3