Additional file 3 of Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease

Additional file 3: Supplementary Fig. 3. Memory function in 4 months old SPF, GF and ABX-treated 5xFAD mice. (A) Ratio of right versus left arm entries in the T-maze spontaneous alternation test of 10 months old SPF and GF or (B) SPF and ABX-treated 5xFAD and age-matched WT mice. (C-F) T-maze of 4 months old SPF and GF mice or (G-J) SPF and ABX-treated 5xFAD, as well as respective age-matched WT mice. (K-M) Novel object recognition task of 4 months old SPF and GF 5xFAD, as well as age-matched WT mice or (N-P) SPF and ABX-treated 5xFAD, as well as WT mice. Each symbol represents one mouse. Data are presented as mean ± s.e.m. Significant differences were determined by two-way ANOVA followed by Bonferroni’s post-hoc comparison test (*P