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Growth rate of small lung cancers detected on mass CT screening
- Source :
- The British Journal of Radiology. 73:1252-1259
- Publication Year :
- 2000
- Publisher :
- British Institute of Radiology, 2000.
-
Abstract
- CT has recently been used in mass screening for lung cancer. Small cancers have been identified but the growth characteristics of these lesions are not fully understood. We identified 82 primary cancers in our 3-year mass CT screening programme, of which 61 were examined in the present study. The volume doubling time (VDT) was calculated based on the exponential model using successive annual CT images or follow-up CT images. All cases were also examined in the hospital by high resolution CT (HRCT). Lesions were divided into three types based on HRCT characteristics: type G (n = 19), ground glass opacity (GGO); type GS (n = 19), focal GGO with a solid central component; and type S (n = 23), solid nodule. 18 (95%) lesions of type G, 18 (95%) of type GS and 7 (30%) of type S were invisible on conventional chest radiographs. The mean size of the tumour was 10 mm, 11 mm and 16 mm for type G, type GS and type S, respectively. Most tumours (80%) were adenocarcinomas; 78% of these were GGO (type G and GS). Mean VDT values were 813 days, 457 days and 149 days for type G, type GS and type S, respectively; these are significantly different from each other (p < 0.05). Our results show that annual mass screening CT for 3 successive years resulted in the identification of a large number of slowly growing adenocarcinomas that were not visible on chest radiographs.
- Subjects :
- Adult
Male
Lung Neoplasms
Time Factors
Radiography
Volume Doubling Time
Adenocarcinoma
Ground-glass opacity
Japan
Humans
Mass Screening
Medicine
Doubling time
Radiology, Nuclear Medicine and imaging
Carcinoma, Small Cell
Lung cancer
Mass screening
Aged
Aged, 80 and over
Lung
business.industry
General Medicine
Middle Aged
medicine.disease
medicine.anatomical_structure
Female
medicine.symptom
Tomography, X-Ray Computed
business
Nuclear medicine
Follow-Up Studies
Subjects
Details
- ISSN :
- 1748880X and 00071285
- Volume :
- 73
- Database :
- OpenAIRE
- Journal :
- The British Journal of Radiology
- Accession number :
- edsair.doi.dedup.....18017427ef2bbc8a0a395ef4a35b79fc