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The effect of dexmedetomidine as an adjuvant to ropivacaine on the bispectral index for supraclavicular brachial plexus block
- Source :
- Korean Journal of Anesthesiology, Korean Journal of Anesthesiology, Vol 68, Iss 1, Pp 32-36 (2015)
- Publication Year :
- 2015
- Publisher :
- The Korean Society of Anesthesiologists, 2015.
-
Abstract
- Background The aim of this study was to evaluate the sedative effect of dexmedetomidine (DEX) added to ropivacaine for supraclavicular brachial plexus block (BPB) using the bispectral index (BIS). Methods Sixty patients (American Society of Anesthesiologists physical status 1 or 2, aged 20-65 years) undergoing wrist and hand surgery under supraclavicular BPB were randomly allocated to two groups. Ultrasound-guided supraclavicular BPB was performed with 40 ml of ropivacaine 0.5% and 1 µg/kg of DEX (Group RD) or 0.01 ml/kg of normal saline (Group R). The primary endpoint was the BIS change during 60 min after block. The secondary endpoint was the change in the mean arterial blood pressure (MAP), heart rate (HR), and SpO2 and the onset time and duration of the sensory and motor block. Results In Group RD, the BIS decreased significantly until 30 min after the block (69.2 ± 13.7), but remained relatively constant to 60 min (63.8 ± 15.3). The MAP, HR and BIS were significantly decreased compared with Group R. The onset time of the sensory and motor block were significantly faster in Group RD than in Group R. The duration of the sensory and motor block were significantly increased in Group RD. Conclusions DEX added to ropivacaine for brachial plexus block induced sedation that corresponds to a BIS value of 60 from which patients are easily awakened in a lucid state. In addition, perineural DEX shortened the onset time and prolonged the duration of the sensory and motor blocks.
- Subjects :
- Clinical Research Article
medicine.medical_specialty
Ropivacaine
business.industry
Sedation
Surgery
lcsh:RD78.3-87.3
Anesthesiology and Pain Medicine
Blood pressure
Bispectral index
lcsh:Anesthesiology
Anesthesia
Heart rate
medicine
medicine.symptom
Dexmedetomidine
Brachial plexus
business
medicine.drug
Brachial plexus block
Subjects
Details
- ISSN :
- 20057563 and 20056419
- Volume :
- 68
- Database :
- OpenAIRE
- Journal :
- Korean Journal of Anesthesiology
- Accession number :
- edsair.doi.dedup.....17a76b71f9fbb6c550a3b29fa6ea02c2