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Association between serum magnesium concentration and metabolic syndrome, diabetes, hypertension and hyperuricaemia in knee osteoarthritis: a cross-sectional study in Hunan Province, China
- Source :
- BMJ open. 8(9)
- Publication Year :
- 2018
-
Abstract
- ObjectivesTo examine the associations between serum magnesium (Mg) concentration with the prevalence of metabolic syndrome (MetS), diabetes mellitus (DM), hypertension (HP) and hyperuricaemia (HU) in patients with radiographic knee osteoarthritis (OA).MethodsThe present study was conducted at the Health Management Center of Xiangya Hospital. Radiographic OA was evaluated for patients aged over 40 years with basic characteristics and blood biochemical assessment. Serum Mg concentration was measured using the chemiluminescence method. MetS, DM, HP and HU were diagnosed based on standard protocols. The associations between serum Mg concentration with MetS, DM, HP and HU were evaluated by conducting multivariable adjusted logistic regression.ResultsA total of 962 patients with radiographic knee OA were included. Compared with the lowest quintile, the multivariable adjusted ORs and related 95% CIs of DM were 0.40 (95% CI 0.23 to 0.70, p=0.001), 0.33 (95% CI 0.18 to 0.60, pConclusionsThe serum Mg concentration was inversely associated with the prevalence of MetS, DM and HU in patients with radiographic knee OA.Level of evidenceLevel III, cross-sectional study.
- Subjects :
- Male
medicine.medical_specialty
China
Cross-sectional study
Osteoarthritis
Comorbidity
Hyperuricemia
Logistic regression
03 medical and health sciences
0302 clinical medicine
Diabetes mellitus
Internal medicine
medicine
Diabetes Mellitus
Prevalence
Humans
In patient
Magnesium
030212 general & internal medicine
030203 arthritis & rheumatology
Metabolic Syndrome
business.industry
General Medicine
Middle Aged
Osteoarthritis, Knee
medicine.disease
Cross-Sectional Studies
Hypertension
Female
Level iii
Metabolic syndrome
business
Subjects
Details
- ISSN :
- 20446055
- Volume :
- 8
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- BMJ open
- Accession number :
- edsair.doi.dedup.....1790c87b4c1e7db12a1e1add13eafc25