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Real-time reading in mammography breast screening
- Source :
- La Radiologia medica. 112(2)
- Publication Year :
- 2006
-
Abstract
- This study was undertaken to assess the role of real-time reading in the mammography screening programme carried out at the Hospital of Marzana, Verona, Italy.During the 5-year period 1999-2004, 54,472 women attended the screening programme (32,291 first calls: unadjusted uptake 41.4%, adjusted uptake 50.3%; 21,551 2- year routine recalls: unadjusted uptake 86.4%, adjusted uptake 89.9%). Further diagnostic investigations [(FDI), imaging and cytohistological] were performed immediately after real-time reading of the screening mammograms (FDI rate among first calls 10.9%; FDI rate among 2-year recalls 5.4%). Overall, cytohistological FDI were requested in 27% of imaging FDI, with a clear prevalence of cytological [fine-needle aspiration cytology (FNAC) 87%] over histological procedures [core needle biopsy (CNB) 11%; vacuum aspiration biopsy (VAB) 2%].Imaging FDI proved to be conclusive in 73%. Cytohistological FDI led to the use of surgical biopsy (SB) in 39.5% (ratio between benign and malignant SB: 0.19/first calls, 0.14/2-year recalls). There were a total of 427 screen-detected breast cancers (BC), with a very good breast cancer detection rate (BCDR/first calls 9.7 per thousand; BCDR/2-year recalls 5.1 per thousand). In the 427 screen-detected BC, the incidence of pTis, pT1a,b cancers was 59.6% (diagnostic anticipation); the incidence of pN0 cancers was 61.2%; the incidence of conservative surgical procedures was 78.6%. In interval cancers, the false negative rate was 8.3% only, whereas the proportional incidence was very low indeed (14% first year; 38% second year).The high sensitivity exhibited by the Marzana mammography screening programme suggests that the value of real-time reading should be validated by other programmes adopting a similar approach.
- Subjects :
- medicine.medical_specialty
media_common.quotation_subject
Biopsy
MEDLINE
Breast Neoplasms
Sensitivity and Specificity
Reading (process)
Medicine
Breast screening
Mammography
Humans
Mass Screening
Radiology, Nuclear Medicine and imaging
Medical physics
Neuroradiology
media_common
Neoplasm Staging
medicine.diagnostic_test
business.industry
real-time reading
Interventional radiology
General Medicine
Italy
Female
Radiology
Mammography screening
business
mammography breast screening
Subjects
Details
- ISSN :
- 00338362
- Volume :
- 112
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- La Radiologia medica
- Accession number :
- edsair.doi.dedup.....177bc85ea83e9a442b85511ff1d843cf