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Natural compounds with Wnt signal modulating activity
- Source :
- Natural product reports. 32(12)
- Publication Year :
- 2015
-
Abstract
- Covering: up to 2015 The Wnt signalling pathway is essential in many biological processes. The Wnt signal is associated with several diseases, particularly cancer and neurodegenerative diseases. Recently, high-throughput screening systems have been developed to rapidly identify compounds, including natural compounds, that target the Wnt signal. Some studies on natural modulators of the Wnt signal have also suggested their possible target. This review highlights some important natural compounds reported to regulate Wnt activity and describes their possible mechanism of action.
- Subjects :
- Biological Products
Molecular Structure
Organic Chemistry
Wnt signaling pathway
LRP6
Wnt signalling
Neurodegenerative Diseases
Biology
biology.organism_classification
Biochemistry
Signal
Cell biology
Wnt Proteins
Mechanism of action
Neoplasms
Drug Discovery
medicine
Animals
Humans
medicine.symptom
Signal transduction
Zebrafish
Wnt Signaling Pathway
Signal Transduction
Subjects
Details
- ISSN :
- 14604752
- Volume :
- 32
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Natural product reports
- Accession number :
- edsair.doi.dedup.....1757faee35dddec7133aee7eca2a352b