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The genetic heritage of Alpine local cattle breeds using genomic SNP data
- Source :
- Genetics Selection Evolution, Vol 52, Iss 1, Pp 1-12 (2020), Genetics, Selection, Evolution : GSE, Genetics Selection Evolution, Genetics Selection Evolution, BioMed Central, 2020, 52 (1), pp.40. ⟨10.1186/s12711-020-00559-1⟩
- Publication Year :
- 2020
- Publisher :
- BMC, 2020.
-
Abstract
- Background Assessment of genetic diversity and population structure provides important control metrics to avoid genetic erosion, inbreeding depression and crossbreeding between exotic and locally-adapted cattle breeds since these events can have deleterious consequences and eventually lead to extinction. Historically, the Alpine Arc represents an important pocket of cattle biodiversity with a large number of autochthonous breeds that provide a fundamental source of income for the entire regional economy. By using genotype data from medium-density single nucleotide polymorphism (SNP) arrays, we performed a genome-wide comparative study of 23 cattle populations from the Alpine Arc and three cosmopolitan breeds. Results After filtering, we obtained a final genotyping dataset consisting of 30,176 SNPs for 711 individuals. The local breeds showed high or intermediate values of genetic diversity compared to the highly selected cosmopolitan breeds. Patterns of genetic differentiation, multidimensional scaling, admixture analysis and the constructed phylogenetic tree showed convergence, which indicates the presence of gene flow among the breeds according to both geographic origin and historical background. Among the most differentiated breeds, we identified the modern Brown cattle. In spite of admixture events, several local breeds have preserved distinctive characteristics, which is probably due to differences in genetic origin and geographic location. Conclusions This study represents one of the most comprehensive genome-wide analysis of the Alpine cattle breeds to date. Using such a large dataset that includes the majority of the local breeds found in this region, allowed us to expand knowledge on the evaluation and status of Alpine cattle biodiversity. Our results indicate that although many of the analyzed local breeds are listed as endangered, they still harbor a large amount of genetic diversity, even when compared to some cosmopolitan breeds. This finding, together with the reconstruction of the phylogeny and the relationships between these Alpine Arc cattle breeds, provide crucial insights not only into the improvement of genetic stocks but also into the implementation of future conservation strategies.
- Subjects :
- breeds
genomic SNP data
Genotype
lcsh:QH426-470
[SDV]Life Sciences [q-bio]
Biodiversity
Endangered species
Biology
Crossbreed
Polymorphism, Single Nucleotide
Genetic diversity
Gene flow
Evolution, Molecular
Settore AGR/17 - Zootecnica Generale E Miglioramento Genetico
03 medical and health sciences
cattle biodiversity
cattle, biodiversity, breeds, Italian Alps
Genetics
Inbreeding depression
Alpine Cattle breeds
Animals
Cattle Breeds, genomic SNP data, Bovine SNP, Alpine Cattle breeds, SNP Arrays, cattle biodiversity
Genetic erosion
Ecology, Evolution, Behavior and Systematics
Phylogeny
biodiversity
030304 developmental biology
lcsh:SF1-1100
2. Zero hunger
0303 health sciences
Phylogenetic tree
0402 animal and dairy science
Italian Alps
04 agricultural and veterinary sciences
General Medicine
15. Life on land
Cattle Breeds
040201 dairy & animal science
lcsh:Genetics
local cattle
Evolutionary biology
Bovine SNP
Animal Science and Zoology
Cattle
lcsh:Animal culture
SNP array
SNP Arrays
Research Article
Subjects
Details
- Language :
- German
- ISSN :
- 12979686 and 0999193X
- Volume :
- 52
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Genetics Selection Evolution
- Accession number :
- edsair.doi.dedup.....174245a935624c30b97d14e3bde1bb18