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Ratio of early diastolic tricuspid inflow to tricuspid lateral annulus velocity reflects pulmonary regurgitation severity but not right ventricular diastolic function in children with repaired Tetralogy of Fallot
- Source :
- Pediatric cardiology. 34(5)
- Publication Year :
- 2012
-
Abstract
- The current study assessed relationships between the ratio of early diastolic tricuspid inflow to tricuspid lateral annular velocity (tricuspid E/e') and right ventricular (RV) function in children after tetralogy of Fallot (TOF) repair. The RV function of 25 asymptomatic children with surgically repaired TOF (age 3.3 ± 2.0 years) was assessed by echocardiography and cardiac catheterization. Right ventricular end-diastolic pressure and volume (RVEDP and RVEDV), systolic pressure, and ejection fraction, as well as mean pulmonary arterial pressure, mean right atrial pressure (RAP), and the severity of both pulmonary regurgitation (PR) and tricuspid regurgitation (TR) were assessed in terms of the contribution to tricuspid E/e'. Univariate analysis discovered a relationship between tricuspid E/e' and RVEDV (R(2) = 0172), pressure half-time of PR (PR-PHT) (R(2) = 0.173), and TR grade (R(2) = 0.145) (p < 0.01 for each). After multivariate adjustment, PR-PHT was significantly associated with tricuspid E/e' (β = 0.210; p < 0.001). Tricuspid E/e' was not significantly associated with RVEDP or RAP. In conclusion, tricuspid E/e' does not indicate RV diastolic function but reflects the severity of PR in asymptomatic children after TOF repair.
- Subjects :
- Male
congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Cardiac Catheterization
medicine.medical_treatment
Diastole
Asymptomatic
Severity of Illness Index
Internal medicine
medicine
Humans
cardiovascular diseases
Child
Tetralogy of Fallot
Cardiac catheterization
Tricuspid valve
Ejection fraction
business.industry
Infant
medicine.disease
Pulmonary Valve Insufficiency
Cardiac surgery
medicine.anatomical_structure
Blood pressure
Echocardiography
Child, Preschool
Pediatrics, Perinatology and Child Health
Heart Function Tests
cardiovascular system
Cardiology
Female
Tricuspid Valve
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Blood Flow Velocity
Subjects
Details
- ISSN :
- 14321971
- Volume :
- 34
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Pediatric cardiology
- Accession number :
- edsair.doi.dedup.....1717768db51de80ddd89d6fc5813f814