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A Naturalistic Paradigm to Investigate Postencoding Neural Activation Patterns in Relation to Subsequent Voluntary and Intrusive Recall of Distressing Events
- Source :
- Biological psychiatry. Cognitive neuroscience and neuroimaging, 7(10), 960-969. Elsevier Inc.
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- BackgroundWhile neuroimaging has provided insights into the formation of episodic memories in relation to voluntary memory recall, less is known about neural mechanisms that cause memories to occur involuntarily, for example, as intrusive memories of trauma. Here, we investigated brain activity shortly after viewing distressing events as a function of whether memories for those events later intruded involuntarily. The postencoding period is particularly important because it is a period when clinical interventions could be applied.MethodsA total of 32 healthy volunteers underwent functional magnetic resonance imaging while viewing distressing film clips, interspersed with 5 minutes of awake (postencoding) rest. Voluntary memories of the films were assessed using free recall and verbal and visual recognition tests after a week, while intrusive (involuntary) memories were recorded in a diary throughout that week.ResultsWhen analyzing functional magnetic resonance imaging responses related to watching the films, we replicated findings that those “hotspots” (salient moments within the films) that would later become intrusive memories elicited higher activation in parts of the brain’s salience network. Surprisingly, while the postencoding persistence of multivoxel correlation structures associated with entire film clips predicted subsequent voluntary recall, there was no evidence that they predicted subsequent intrusions.ConclusionsResults replicate findings regarding the formation of intrusive memories during encoding and extend findings regarding the consolidation of information in postencoding rest in relation to voluntary memory. While we provided a first step using a naturalistic paradigm, further research is needed to elucidate the role of postencoding neural processes in the development of intrusive memories.
- Subjects :
- Brain activity and meditation
Memory, Episodic
Rest
Cognitive Neuroscience
Involuntary memory
Psykiatri
medicine
Humans
Radiology, Nuclear Medicine and imaging
Episodic memory
Biological Psychiatry
Psychiatry
medicine.diagnostic_test
Recall
Neurosciences
Recognition, Psychology
Magnetic Resonance Imaging
Free recall
Mental Recall
Memory consolidation
Neurology (clinical)
Functional magnetic resonance imaging
Psychology
Neurovetenskaper
Cognitive psychology
Mental image
Subjects
Details
- ISSN :
- 24519022
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
- Accession number :
- edsair.doi.dedup.....16ccec76ee4a5a99e05735a1fbfa3898