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Cutaneous side effects of vemurafenib: a case report and discussion
- Source :
- Wiener Medizinische Wochenschrift. 163:376-379
- Publication Year :
- 2013
- Publisher :
- Springer Science and Business Media LLC, 2013.
-
Abstract
- In 2011, the FDA approved the drug vemurafenib, a potent kinase inhibitor with specificity for the BRAF V600E mutation, for the treatment of metastatic melanoma. While this drug is otherwise well-tolerated, many patients develop cutaneous toxicities. This report demonstrates multiple cutaneous toxicities in a patient while undergoing treatment with vemurafenib.
- Subjects :
- Reoperation
Drug
medicine.medical_specialty
Indoles
Skin Neoplasms
Metastatic melanoma
media_common.quotation_subject
Pharmacology toxicology
Neoplasms, Multiple Primary
Duodenal Neoplasms
medicine
Humans
Vemurafenib
Melanoma
Aged
Neoplasm Staging
media_common
Leg
Sulfonamides
Sentinel Lymph Node Biopsy
business.industry
Geriatrics gerontology
Neoplasms, Second Primary
General Medicine
Hand
Combined Modality Therapy
Dermatology
BRAF V600E
Chemotherapy, Adjuvant
Lymphatic Metastasis
Mutation (genetic algorithm)
Carcinoma, Squamous Cell
Lymph Node Excision
Female
Drug Eruptions
Warts
business
medicine.drug
Subjects
Details
- ISSN :
- 1563258X and 00435341
- Volume :
- 163
- Database :
- OpenAIRE
- Journal :
- Wiener Medizinische Wochenschrift
- Accession number :
- edsair.doi.dedup.....16b961a6c0432f14a2b3028bf8520694