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Red cell–bound antibodies and transfusion requirements in hospitalized patients with COVID-19
- Source :
- Blood
- Publication Year :
- 2020
- Publisher :
- American Society of Hematology, 2020.
-
Abstract
- Berzuini et al report the observation that nearly half of patients with COVID-19 tested at their blood center had a positive direct antiglobulin test (DAT). However, eluates did not react with any test cells but did react with red cells from other patients with COVID-19 that were DAT negative. This suggests that COVID-19 may modulate the red cell membrane and present novel antigenic epitopes.
- Subjects :
- Male
Blood transfusion
Erythrocytes
Hospitalized patients
medicine.medical_treatment
030204 cardiovascular system & hematology
Biochemistry
Immunoglobulin G
0302 clinical medicine
Coombs test
Medicine
Letter to Blood
Aged, 80 and over
medicine.diagnostic_test
biology
Anemia
Hematology
Middle Aged
Coombs Test
030220 oncology & carcinogenesis
Female
Antibody
Coronavirus Infections
Erythrocyte Transfusion
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Patients
Immunology
Pneumonia, Viral
Antibodies
03 medical and health sciences
Betacoronavirus
Internal medicine
mental disorders
Humans
Blood Transfusion
Pandemics
Aged
Autoantibodies
Red Cell
business.industry
SARS-CoV-2
COVID-19
Cell Biology
medicine.disease
biology.protein
business
Subjects
Details
- Language :
- English
- ISSN :
- 15280020 and 00064971
- Volume :
- 136
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Blood
- Accession number :
- edsair.doi.dedup.....1664af0753d337f5a6ede237ccab5e65