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The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine
- Source :
- Molecules, Vol 20, Iss 11, Pp 19775-19788 (2015), Molecules
- Publication Year :
- 2015
- Publisher :
- MDPI AG, 2015.
-
Abstract
- Since its discovery, the Phe-Phe motif has gained in popularity as a minimalist building block to drive the self-assembly of short peptides and their analogues into nanostructures and hydrogels. Molecules based on the Phe-Phe motif have found a range of applications in nanomedicine, from drug delivery and biomaterials to new therapeutic paradigms. Here we discuss the various production methods for this class of compounds, and the characterization, nanomorphologies, and application of their self-assembled nanostructures. We include the most recent findings on their remarkable properties, which hold substantial promise for the creation of the next generation nanomedicines.
- Subjects :
- Amino Acid Motifs
Pharmaceutical Science
diphenylalanine
Nanotechnology
Peptide
Review
Analytical Chemistry
lcsh:QD241-441
chemistry.chemical_compound
Drug Delivery Systems
lcsh:Organic chemistry
Drug Discovery
nanostructures
Physical and Theoretical Chemistry
Diphenylalanine
self-assembly, peptides, nanomaterials, nanomedicine
nanomaterials
hydrogels
chemistry.chemical_classification
Drug Carriers
Chemistry
Organic Chemistry
Dipeptides
self-assembly
Combinatorial chemistry
nanomedicine
Chemistry (miscellaneous)
Drug delivery
Self-healing hydrogels
peptides
Molecular Medicine
Nanomedicine
Motif (music)
Self-assembly
Drug carrier
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 20
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Molecules
- Accession number :
- edsair.doi.dedup.....16557a0a466a2c0c10fde2f6c4c5d580