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Testing the stand-alone microbeam at Columbia University
- Source :
- Radiation protection dosimetry. 122(1-4)
- Publication Year :
- 2006
-
Abstract
- The stand-alone microbeam at Columbia University presents a novel approach to biological microbeam irradiation studies. Foregoing a conventional accelerator as a source of energetic ions, a small, high-specific-activity, alpha emitter is used. Alpha particles emitted from this source are focused using a compound magnetic lens consisting of 24 permanent magnets arranged in two quadrupole triplets. Using a 'home made' 6.5 mCi polonium source, a 1 alpha particle s(-1), 10 microm diameter microbeam can, in principle, be realised. As the alpha source energy is constant, once the microbeam has been set up, no further adjustments are necessary apart from a periodic replacement of the source. The use of permanent magnets eliminates the need for bulky power supplies and cooling systems required by other types of ion lenses and greatly simplifies operation. It also makes the microbeam simple and cheap enough to be realised in any large lab. The Microbeam design as well as first tests of its performance, using an accelerator-based beam are presented here.
- Subjects :
- Materials science
Technology Assessment, Biomedical
Universities
Static Electricity
Columbia university
Cell Culture Techniques
New York
Nanotechnology
Cell Separation
Radiation Dosage
Optics
Magnetic lens
Radiology, Nuclear Medicine and imaging
Heavy Ions
Radiometry
Common emitter
Radiation
Miniaturization
Radiological and Ultrasound Technology
business.industry
Public Health, Environmental and Occupational Health
General Medicine
Alpha particle
Microbeam
Equipment Design
Equipment Failure Analysis
Magnet
Quadrupole
Particle Accelerators
business
Beam (structure)
Subjects
Details
- ISSN :
- 01448420
- Volume :
- 122
- Issue :
- 1-4
- Database :
- OpenAIRE
- Journal :
- Radiation protection dosimetry
- Accession number :
- edsair.doi.dedup.....164009ae95f5ff62ab4a9e9b0465f4a2