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Magnetic resonance imaging in the evaluation of clinical trials in multiple sclerosis

Authors :
David K.B. Li
Joel Oger
R. A. Koopmans
Elizabeth Tanton
Donald W. Paty
Lorne F. Kastrukoff
Gou Jun Zhao
Source :
Annals of neurology.
Publication Year :
1994

Abstract

Magnetic resonance imaging (MRI) provides an objective method of evaluating multiple sclerosis clinical trials and is at least five times more sensitive to disease activity. In a recent clinical trial, MRI was also approximately twice as sensitive as clinical measurements to the treatment effect of a drug.

Details

ISSN :
03645134
Database :
OpenAIRE
Journal :
Annals of neurology
Accession number :
edsair.doi.dedup.....163f5aec6254eff7ae8e472dbb9a34a6