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Do subjective memory complaints herald the onset of mild cognitive impairment in Parkinson disease?
- Source :
- Journal of geriatric psychiatry and neurology. 27(4)
- Publication Year :
- 2014
-
Abstract
- Background: Longitudinal studies on healthy participants have shown that subjective memory impairment (defined as subjective cognitive complaints with normal cognitive objective performance) might be a strong predictor of mild cognitive impairment (MCI). Parkinson disease (PD) also manifests cognitive disturbances, but whether subjective memory complaints may predict the development of MCI in PD has not yet been explored. Methods: We prospectively screened newly diagnosed, untreated patients with PD in order to evaluate whether subjective memory complaints may predict development of MCI over a 2-year follow-up evaluation. Results: We enrolled 76 de novo untreated patients with PD. Of the 76 patients, 23 (30.3%) complained memory issues. Among the patients cognitively unimpaired at baseline, those with subjective complaints were more likely to develop MCI at follow-up. The regression model confirmed that presence of subjective memory complaints at baseline was an independent predictor of development of MCI at follow-up. Discussion: This is the first prospective study to explore the relationship between subjective and objective cognitive deficits in newly diagnosed, untreated patients. Our results provide preliminary evidence that subjective memory complaints might predict future development of MCI.
- Subjects :
- Questionnaires
Male
Mild Cognitive Impairment
medicine.medical_specialty
Logistic Model
Predictive Value of Test
Newly diagnosed
Disease
Subjective memory
Audiology
Neuropsychological Tests
Independent predictor
Follow-Up Studie
Memory
Predictive Value of Tests
cognitive testing
Surveys and Questionnaires
medicine
Surveys and Questionnaire
Humans
Cognitive Dysfunction
Prospective Studies
Prospective cohort study
Psychiatry
Cognitive impairment
cognitive impairment
Aged
Psychiatric Status Rating Scales
Memory Disorders
Cognition
Parkinson Disease
Psychiatric Status Rating Scale
Middle Aged
Educational Statu
Cognitive test
Prospective Studie
Logistic Models
Psychiatry and Mental Health
Disease Progression
Parkinson disease
Educational Status
Female
Follow-Up Studies
Neuropsychological Test
Neurology (clinical)
Geriatrics and Gerontology
Psychology
Human
Memory Disorder
Subjects
Details
- ISSN :
- 08919887
- Volume :
- 27
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of geriatric psychiatry and neurology
- Accession number :
- edsair.doi.dedup.....1617ba2eca0134745a8912438a0b73bc