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The microcirculation in hypoxia: The center of the battlefield for oxygen
- Source :
- Clinical Hemorheology and Microcirculation. 63:169-172
- Publication Year :
- 2016
- Publisher :
- IOS Press, 2016.
-
Abstract
- In the past years the microcirculation has gained increasing attention not only by basic scientists, but also by clinicians and translational researchers. In the clinical scenario, it has been convincingly described that the microcirculation is a key predictor of outcome and of central pathophysiological relevance. A vast body of evidence demonstrates the central role of the smallest vessels in inflammation, hyperviscosity, cell-cell-interaction, endothelial function, tissue edema, hemodynamic and blood flow regulation and its important role in the interaction with soluble factors. A central feature of different diseases and a strong regulator of different changes is hypoxia, the lack of oxygen. Also the microcirculation is on one hand a central component responding with dynamic changes to hypoxia but also the central place where hypoxia mediates its unfavorable effects. These changes and associated interactions are the topic of this special thematic issue "Hypoxia" in Clinical Hemorheology and Microcirculation and it seems logical that important and relevant findings are presented.
- Subjects :
- Tissue edema
Physiology
Hemodynamics
Hyperviscosity
Inflammation
030204 cardiovascular system & hematology
030218 nuclear medicine & medical imaging
Microcirculation
03 medical and health sciences
Oxygen Consumption
0302 clinical medicine
Battlefield
Physiology (medical)
medicine
Humans
business.industry
Hematology
Hypoxia (medical)
Cell Hypoxia
Oxygen
Hemorheology
Immunology
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Neuroscience
Subjects
Details
- ISSN :
- 18758622 and 13860291
- Volume :
- 63
- Database :
- OpenAIRE
- Journal :
- Clinical Hemorheology and Microcirculation
- Accession number :
- edsair.doi.dedup.....16059fc4019f3d1aa57ba19321d3f84a