Additional file 1: of Reduced penetrance of the PSEN1 H163Y autosomal dominant Alzheimer mutation: a 22-year follow-up study

Longitudinal z-scores for the RAVL total learning test measuring episodic memory in brothers A and B. The scatterplot shows episodic memory as evaluated by the RAVL total learning test and expressed in z-score values versus years to the expected clinical onset of Alzheimer’s disease. The longitudinal trajectories are illustrated by LOESS curves for brothers A and B. RAVL Rey Auditory Verbal Learning. (PDF 222 kb)