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Comprehensive evaluation of the risk of lactational mastitis in Chinese women: combined logistic regression analysis with receiver operating characteristic curve
- Source :
- Bioscience Reports
- Publication Year :
- 2020
- Publisher :
- Portland Press Ltd., 2020.
-
Abstract
- Objective: To identify the potential risk factors for acute mastitis during lactation comprehensively. Subsequently, to evaluate logistic regression model in predicting the risk of lactational mastitis in Chinese women by applying receiver operating characteristic (ROC) curve. Methods: A case–control study among Chinese women enrolled 652 patients with mastitis and 581 healthy women with breastfeeding experience as control. The retrospective information was obtained by questionnaires that included medical history of pregnancy, delivery, puerperium and breastfeeding behaviors. Univariate analysis and multivariate logistic regression model were performed to investigate the relationship between these factors and the occurrence of lactational mastitis. Using ROC curve to evaluate the prognostic value of these selected indicators in the risk of acute mastitis. Results: The multivariate logistic regression analysis showed that the primiparity (P < 0.001), mastitis in previous breastfeeding (P < 0.001), nipple’s heteroplasia (P < 0.001), cracked nipple (P < 0.001), breast trauma by external force (P = 0.002), lateral position (P = 0.007), breast pump (P = 0.039), nipple sucking (P = 0.007), sleep with sucking (P = 0.007), and tongue-tie (P = 0.013) were risk variables independently and significantly related with mastitis. While vaginal delivery (P = 0.015), clean nipple before breastfeeding (P = 0.015), first contact with child within 1 h (P = 0.027) were protective factors. The ROC analysis demonstrated that the area under the curve of model 2 was 0.8122 (95%CI = 0.7885–0.8360), which stated that the model presented a high sensitivity and specificity. Conclusion: By means of collecting and summarizing the risk factors associated with the occurrence of breast mastitis in Chinese women, we established risk discriminant model to identify and warn the individuals susceptible to acute mastitis early, which will allow practitioners to provide appropriate management advice and effective individual care.
- Subjects :
- Adult
0301 basic medicine
Immunology & Inflammation
China
medicine.medical_specialty
Breastfeeding
Biophysics
Mastitis
Logistic regression
Biochemistry
Molecular Bases of Health & Disease
law.invention
03 medical and health sciences
0302 clinical medicine
Asian People
law
medicine
Humans
Lactation
Logistic Regression
030212 general & internal medicine
Molecular Biology
Diagnostics & Biomarkers
Research Articles
Retrospective Studies
Pregnancy
Univariate analysis
030109 nutrition & dietetics
Receiver operating characteristic
business.industry
Vaginal delivery
Obstetrics
Cell Biology
Prognosis
medicine.disease
ROC curve
Breast Feeding
Logistic Models
Risk factors
Case-Control Studies
Female
Breast pump
business
Subjects
Details
- ISSN :
- 15734935 and 01448463
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Bioscience Reports
- Accession number :
- edsair.doi.dedup.....15edcbaa9f27320c51e314b47da9ac62
- Full Text :
- https://doi.org/10.1042/bsr20190919