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Agreement between fixed-ratio and lower limit of normal spirometry interpretation protocols decreases with age: is there a need for a new GOLD standard?
- Source :
- Journal of occupational and environmental medicine. 55(7)
- Publication Year :
- 2013
-
Abstract
- Objectives: To assess concordance between the fixed 70% ratio cutoff point with the fixed percent predicted values (Fixed-ratio) and the lower limit of normal (LLN) algorithms in interpreting spirometry results in an older population. Methods: Spirometries were interpreted using Third National Health and Nutrition Examination Survey reference equations for 2319 workers. Results: The Fixed-ratio algorithm characterized 34.5% (n = 801) results as abnormal, compared with 29.7% (n = 689) by the LLN. There were almost twice as many obstructive and mixed airways spirometries identified under the Fixed-ratio compared to LLN. Rates of restrictive pattern physiology were virtually the same under each algorithm. Overall agreement between the algorithms decreased with age from “almost perfect” for those younger than 60 years to “substantial” for those older than 80 years. Conclusions: This study found age-related discordance between two algorithms possibly related to the lack of reference equations and standards for individuals older than 80 years.
- Subjects :
- Spirometry
Adult
Male
Pediatrics
medicine.medical_specialty
National Health and Nutrition Examination Survey
Concordance
Vital Capacity
Lower limit
Decision Support Techniques
Forced Expiratory Volume
Statistics
Medicine
Humans
Lung Diseases, Obstructive
Aged
Aged, 80 and over
Normal spirometry
medicine.diagnostic_test
business.industry
Public Health, Environmental and Occupational Health
Age Factors
Reproducibility of Results
Gold standard (test)
Middle Aged
Reference Standards
Nutrition Surveys
Logistic Models
Multivariate Analysis
Female
Cutoff point
business
Fixed ratio
Respiratory Insufficiency
Algorithms
Subjects
Details
- ISSN :
- 15365948
- Volume :
- 55
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of occupational and environmental medicine
- Accession number :
- edsair.doi.dedup.....15dba7c1614570432fdd353054c9cbcb