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Enzymatic synthesis of chiral intermediates for pharmaceuticals
- Source :
- Journal of Industrial Microbiology and Biotechnology. 30:252-259
- Publication Year :
- 2003
- Publisher :
- Oxford University Press (OUP), 2003.
-
Abstract
- There has been an increasing awareness of the enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enatioselective manner. Chiral intermediates are in high demand by pharmaceutical industries for the preparation bulk drug substances. In this review article, microbial/enzymatic processes for the synthesis of chiral intermediates for antihypertensive drugs, melatonin receptor agonists, and beta3-receptor receptor agonists are described.
- Subjects :
- chemistry.chemical_classification
Chemistry, Pharmaceutical
Receptors, Melatonin
Receptors, Cytoplasmic and Nuclear
Adrenergic beta-3 Receptor Agonists
Receptors, Cell Surface
Stereoisomerism
Bioengineering
Adrenergic beta-Agonists
Enzymatic synthesis
Applied Microbiology and Biotechnology
Bulk drug
Melatonin receptor
Enzymes
Enzyme
chemistry
Biocatalysis
Organic chemistry
Antihypertensive Agents
Biotransformation
Biotechnology
Subjects
Details
- ISSN :
- 14765535 and 13675435
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Journal of Industrial Microbiology and Biotechnology
- Accession number :
- edsair.doi.dedup.....158b016c82fa7a54dbd6b58c49980d87