Supplementary Materials and Methods, Supplementary Figure S1, Supplementary Figure S2, Supplementary Figure S3, Supplementary Figure S4, Supplementary Figure S5 from Inhibition of Importin β1 Augments the Anticancer Effect of Agonistic Anti-Death Receptor 5 Antibody in TRAIL-resistant Tumor Cells

Immunohistochemistry and image analysis, Apoptosis induction in shRNA-transduced importin β1 knockdown HeLa cells with administration of agonistic anti-hDR5 mAb (CS-1008) in vivo, Antitumor effect of importin β1 knockdown via atelocollagen delivery of shRNA in combination with CS-1008 on HeLa and HepG2 xenograft models, Effect of importazole on apoptosis induction by rTRAIL in HeLa and HepG2 cells in vitro, Body weights of the mice during the treatment importazole and/or CS-1008 in the experiments presented in Fig. 6, Importin β1 expression in the xenograft tumor tissues dissected from the mice treated with hIgG and doxycycline in the experiments presented in Fig. 3A and B.