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Correlation of CT-based regional cardiac function (SQUEEZ) with myocardial strain calculated from tagged MRI: an experimental study
- Source :
- The International Journal of Cardiovascular Imaging. 32:817-823
- Publication Year :
- 2015
- Publisher :
- Springer Science and Business Media LLC, 2015.
-
Abstract
- The objective of this study was to investigate the correlation between local myocardial function estimates from CT and myocardial strain from tagged MRI in the same heart. Accurate detection of regional myocardial dysfunction can be an important finding in the diagnosis of functionally significant coronary artery disease. Tagged MRI is currently a reference standard for noninvasive regional myocardial function analysis; however, it has practical drawbacks. We have developed a CT imaging protocol and automated image analysis algorithm for estimating regional cardiac function from a few heartbeats. This method tracks the motion of the left ventricular (LV) endocardial surface to produce local function maps: we call the method Stretch Quantification of Endocardial Engraved Zones (SQUEEZ). Myocardial infarction was created by ligation of the left anterior descending coronary artery for 2 h followed by reperfusion in canine models. Tagged and cine MRI scans were performed during the reperfusion phase and first-pass contrast enhanced CT scans were acquired. The average delay between the CT and MRI scans was
- Subjects :
- Cardiac function curve
Pathology
medicine.medical_specialty
Myocardial Infarction
Magnetic Resonance Imaging, Cine
030204 cardiovascular system & hematology
Anterior Descending Coronary Artery
Ventricular Function, Left
Article
Standard deviation
030218 nuclear medicine & medical imaging
Coronary artery disease
Automation
03 medical and health sciences
Dogs
0302 clinical medicine
Predictive Value of Tests
Multidetector Computed Tomography
Linear regression
medicine
Animals
Radiology, Nuclear Medicine and imaging
Myocardial infarction
Cardiac imaging
business.industry
Reproducibility of Results
medicine.disease
Myocardial Contraction
Confidence interval
Biomechanical Phenomena
Disease Models, Animal
Linear Models
Radiographic Image Interpretation, Computer-Assisted
Stress, Mechanical
Cardiology and Cardiovascular Medicine
business
Nuclear medicine
Algorithms
Subjects
Details
- ISSN :
- 15730743 and 15695794
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- The International Journal of Cardiovascular Imaging
- Accession number :
- edsair.doi.dedup.....155323149aa629dd474e745e26d94059