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The Significance of a Pale Area Via Flexible Spectral Imaging Color Enhancement in the Diagnosis of Esophageal Precancerous Lesions and Early-stage Squamous Cancer
- Source :
- Journal of Clinical Gastroenterology
- Publication Year :
- 2019
- Publisher :
- Wolters Kluwer Health, Inc, 2019.
-
Abstract
- Goals The main aim of this study was to investigate the significance of a pale area via flexible spectral imaging color enhancement (FICE) in the diagnosis of esophageal dysplasia and cancer. Background The early diagnosis of esophageal squamous cancer is challenging, and the indication of Lugol's chromoendoscopy has not yet been well established. Study The esophageal mucosa of patients at our endoscopic center were sequentially evaluated with white-light endoscopy and FICE during insertion of the endoscope, followed by staining with Lugol's solution during withdrawal. Patients were divided into 2 groups depending on whether esophageal leukoplakia was detected by white-light endoscopy and 2 groups depending on whether a pale area was detected by FICE. We compared cases of patients with abnormal iodine staining, and cases of dysplasia or cancer in esophageal leukoplakia-or pale area-positive and negative groups. Results Cases of abnormal staining in the esophageal leukoplakia-or pale area-positive group were far more numerous than cases without esophageal leukoplakia or pale area, respectively (P=0.000). Cases of esophageal dysplasia and cancer in the esophageal leukoplakia-or pale area-positive group were far more numerous than cases without esophageal leukoplakia or pale area, respectively (P=0.000). Conclusions Iodine staining should be performed in patients with esophageal leukoplakia or pale areas. Esophageal dysplasia and early-stage cancer were more easily detected in those with esophageal leukoplakia or pale areas.
- Subjects :
- Male
medicine.medical_specialty
Lugol’s solution
Esophageal Mucosa
Endoscope
genetic structures
Esophageal Neoplasms
Fuji intelligent chromoendoscope
Gastroenterology
Chromoendoscopy
03 medical and health sciences
0302 clinical medicine
stomatognathic system
Internal medicine
medicine
Humans
Stage (cooking)
Early Detection of Cancer
Aged
Neoplasm Staging
ONLINE ARTICLES: Original Articles
esophageal leukoplakia
medicine.diagnostic_test
Staining and Labeling
business.industry
Cancer
Iodides
Middle Aged
medicine.disease
Image Enhancement
Staining
Endoscopy
esophageal squamous cell carcinoma
stomatognathic diseases
Dysplasia
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
Esophageal leukoplakia
Esophagoscopy
business
Precancerous Conditions
Subjects
Details
- Language :
- English
- ISSN :
- 15392031 and 01920790
- Volume :
- 53
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Gastroenterology
- Accession number :
- edsair.doi.dedup.....14d1d3fb99855e94498ea61dd0263bb9