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The Oxygen Cascade During Exercise in Health and Disease
- Source :
- Mayo Clin Proc
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- The oxygen transport cascade describes the physiological ‘steps’ that bring atmospheric oxygen into the body where it is delivered and consumed by metabolically active tissue. As such, the oxygen cascade is fundamental to our understanding of exercise in health and disease. Our narrative review will highlight each step of the oxygen transport cascade from inspiration of atmospheric oxygen down to mitochondrial consumption in both healthy active males and females along with clinical conditions. We will focus on how different ‘steps’ interact along with principles of homeostasis, physiological redundancies and adaptation. In particular we highlight some of the parallels between elite athletes and clinical conditions in terms of the oxygen cascade.
- Subjects :
- Adult
Male
chemistry.chemical_element
Disease
030204 cardiovascular system & hematology
Oxygen
Article
03 medical and health sciences
Oxygen Consumption
0302 clinical medicine
Humans
Medicine
Elite athletes
Exercise physiology
Exercise
Aged
Aged, 80 and over
Atmospheric oxygen
business.industry
Oxygen transport
Oxygen–haemoglobin dissociation curve
General Medicine
Middle Aged
Healthy Volunteers
3. Good health
chemistry
Athletes
Cascade
Physical Endurance
Female
business
Neuroscience
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 00256196
- Volume :
- 96
- Database :
- OpenAIRE
- Journal :
- Mayo Clinic Proceedings
- Accession number :
- edsair.doi.dedup.....14cfcf7051dddb27643a661c17b87d28