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Hepatocellular Carcinoma in Transplantable Child-Pugh A Cirrhotics: Should Cost Affect Resection vs Transplantation?
- Source :
- Journal of Gastrointestinal Surgery. 23:1135-1142
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- There is no consensus regarding the optimal surgical treatment for transplantable hepatocellular carcinoma (HCC) patients with well-compensated cirrhosis. Our aim was to compare outcomes between Child-Pugh A (CPA) cirrhotics who underwent liver resection or transplantation for HCC. Clinicopathologic data were retrospectively collected for all surgically treated HCC patients between 7/1992 and 12/2015. Disease-free survival (DFS) and overall survival (OS) were calculated from the time of operation or diagnosis (intention-to-treat analysis including patients removed from the transplant list). The average overall cost including pre-operative and post-operative procedures was calculated for each group. Of the 513 surgically treated HCC patients, 184 had CPA cirrhosis and fulfilled the Milan criteria (MC). Of those, 95 (52%) were resected and 89 (48%) were transplanted. Twenty-two patients were removed from the transplant list. Transplanted patients were younger (p
- Subjects :
- Liver Cirrhosis
Male
Reoperation
medicine.medical_specialty
Carcinoma, Hepatocellular
Cirrhosis
Milan criteria
Gastroenterology
Disease-Free Survival
Lesion
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Hepatectomy
Humans
Aged
Retrospective Studies
business.industry
Liver Neoplasms
Postoperative complication
Hepatitis C
Middle Aged
medicine.disease
Transplant Recipients
Liver Transplantation
Transplantation
Treatment Outcome
030220 oncology & carcinogenesis
Hepatocellular carcinoma
T-stage
Female
030211 gastroenterology & hepatology
Surgery
medicine.symptom
business
Subjects
Details
- ISSN :
- 18734626 and 1091255X
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Journal of Gastrointestinal Surgery
- Accession number :
- edsair.doi.dedup.....14b90893136323f33cce69965b11172f