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Gasotransmitter Heterocellular Signaling
- Source :
- Antioxidants & Redox Signaling. 26:936-960
- Publication Year :
- 2017
- Publisher :
- Mary Ann Liebert Inc, 2017.
-
Abstract
- Significance: The family of gasotransmitter molecules, nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S), has emerged as an important mediator of numerous cellular signal transduction and pathophysiological responses. As such, these molecules have been reported to influence a diverse array of biochemical, molecular, and cell biology events often impacting one another. Recent Advances: Discrete regulation of gasotransmitter molecule formation, movement, and reaction is critical to their biological function. Due to the chemical nature of these molecules, they can move rapidly throughout cells and tissues acting on targets through reactions with metal groups, reactive chemical species, and protein amino acids. Critical Issues: Given the breadth and complexity of gasotransmitter reactions, this field of research is expanding into exciting, yet sometimes confusing, areas of study with significant promise for understanding health and disease. The precise amounts of tissue and cellular...
- Subjects :
- 0301 basic medicine
Physiology
Clinical Biochemistry
Nitric Oxide
Models, Biological
Biochemistry
Nitric oxide
03 medical and health sciences
chemistry.chemical_compound
Mediator
Molecule formation
Animals
Humans
Hydrogen Sulfide
Molecular Biology
General Environmental Science
Carbon Monoxide
Gasotransmitters
Cell Biology
Forum Review Articles
Cellular signal transduction
Cell biology
030104 developmental biology
chemistry
Posttranslational modification
General Earth and Planetary Sciences
Oxidation-Reduction
Signal Transduction
Subjects
Details
- ISSN :
- 15577716 and 15230864
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Antioxidants & Redox Signaling
- Accession number :
- edsair.doi.dedup.....147b267bd8e65b67562d87e9327b3385