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Association between markers of arterial stiffness and atrial fibrillation in the Circulatory Risk in Communities Study (CIRCS)
- Source :
- Atherosclerosis. 263:244-248
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Background and aims Limited evidence is available on the association between markers of arterial stiffness and the prevalence of atrial fibrillation among Asian populations. Therefore, we examined those associations in the Japanese population. Methods We conducted a cross-sectional population-based study of 4264 men and women aged 40–79 years. The augmentation index (AI), a marker of arterial stiffness, was calculated as the ratio of central pulse pressure/brachial pulse pressure, where the AI and central aortic pressure were measured by an automated tonometer: the HEM-9000AI device (Omron Healthcare co., Kyoto, Japan). Atrial fibrillation was estimated by the Minnesota codes using resting electrocardiograph (ECG). Results The prevalence of atrial fibrillation and total arrhythmia were higher with larger AI values. These associations did not change after adjustment for known cardiovascular risk factors. The multivariable odd ratios (95% confidence intervals) in the highest versus lowest tertiles of AI were 3.4 (1.4–8.6, p for trend = 0.008) for atrial fibrillation and 1.8 (1.2–2.7, p for trend = 0.004) for total arrhythmia. There was no association of central or brachial pulse pressure levels with the prevalence of atrial fibrillation or total arrhythmia. Conclusions AI values, but not brachial or central pulse pressures, were positively associated with the prevalence of atrial fibrillation and total arrhythmia, independent of cardiovascular risk factors.
- Subjects :
- Adult
Male
medicine.medical_specialty
Manometry
Population
030204 cardiovascular system & hematology
Electrocardiography
03 medical and health sciences
Vascular Stiffness
0302 clinical medicine
Asian People
Japan
Heart Rate
Risk Factors
Internal medicine
Atrial Fibrillation
Epidemiology
Odds Ratio
Prevalence
medicine
Humans
cardiovascular diseases
030212 general & internal medicine
education
Aged
education.field_of_study
business.industry
Atrial fibrillation
Middle Aged
medicine.disease
Confidence interval
Pulse pressure
Cross-Sectional Studies
Logistic Models
Multivariate Analysis
Circulatory system
cardiovascular system
Aortic pressure
Cardiology
Arterial stiffness
Female
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 00219150
- Volume :
- 263
- Database :
- OpenAIRE
- Journal :
- Atherosclerosis
- Accession number :
- edsair.doi.dedup.....146d558924916b9e5a8b7c36f847b3c3