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Chromium Exposure and Germinal Embryonal Carcinoma: first Two Cases and Review of the Literature
- Publication Year :
- 2015
-
Abstract
- The aim of the study was to determine the potential role of occupational exposures to chromium (Cr) in the onset of extragonadal germinal embryonal carcinoma. The first two cases of workers in a company with Cr exposure are reported. The published scientific literature regarding the topic in peer-reviewed journals including MEDLINE and CancerLit databases was extensively reviewed. Two young patients who were coworkers in the same company, exposed to Cr, developed extragonadal germinal embryonal carcinomas. One of them also developed angiosarcoma of the mediastinum. To the best of our knowledge these are the first two cases of germinal embryonal carcinoma in patients with occupational exposure to Cr The aim of the study was to determine the potential role of occupational exposures to chromium (Cr) in the onset of extragonadal germinal embryonal carcinoma. The first two cases of workers in a company with Cr exposure are reported. The published scientific literature regarding the topic in peer-reviewed journals including MEDLINE and CancerLit databases was extensively reviewed. Two young patients who were coworkers in the same company, exposed to Cr, developed extragonadal germinal embryonal carcinomas. One of them also developed angiosarcoma of the mediastinum. To the best of our knowledge these are the first two cases of germinal embryonal carcinoma in patients with occupational exposure to Cr.
- Subjects :
- Adult
Chromium
Male
Pathology
medicine.medical_specialty
Extragonadal
business.industry
Health, Toxicology and Mutagenesis
Mediastinum
Antineoplastic Agents
Toxicology
medicine.disease
Embryonal carcinoma
Occupational Diseases
medicine.anatomical_structure
Carcinoma, Embryonal
Occupational Exposure
medicine
Humans
In patient
Angiosarcoma
Occupational exposure
Cisplatin
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....1463cf680647a35103016c590d5f87db