Back to Search
Start Over
Associations between symptom severity and well-being among Thai patients with schizophrenia: a cross-sectional analytical study
- Source :
- BMC Psychiatry, Vol 21, Iss 1, Pp 1-9 (2021), BMC Psychiatry
- Publication Year :
- 2021
- Publisher :
- BMC, 2021.
-
Abstract
- Background Severity of symptoms in patients with schizophrenia is a determinant of patient’s well-being, but evidence in low- and middle-income countries is limited. We aimed to measure the symptom severity using objective measurements, the Brief Psychiatric Rating Scale (BPRS) and Clinical Global Impression-Severity scale (CGI-S), and their associations with well-being in patients with schizophrenia. Methods Patients with schizophrenia aged ≥18 years, without active psychosis including no history of hospitalization within the last 6 months, were included. Symptom severity was measured by the clinicians using BPRS and CGI-S. The patients’ well-being was assessed by self-report using the Subjective Well-being under Neuroleptic treatment scale (SWN) as continuous and binary outcomes (categorized into adequate or poor well-being). Correlations between symptom severity (BPRS and CGI-S scores) and well-being (SWN score) were analyzed using Pearson’s correlation. Association between well-being status and BPRS was analyzed using multivariate logistic regression. Results Of 150 patients, BPRS and CGI-S were inversely correlated with SWN score (r = − 0.47; p p r = − 0.51, p p = 0.006, and 4.01; 95%CI 1.38–11.7; p = 0.011, respectively). Conclusion Inverse relationships between symptom severity and well-being score were found. Higher BPRS Affect domain was significantly associated with lower patients’ well-being. The use of BPRS tool into routine clinical practice could serve as an adjunct to physician’s clinical evaluation of patients’ symptoms and may help improve patient’s well-being. Further research on negative symptoms associated with well-being is required.
- Subjects :
- Adult
Quality of life
Psychosis
medicine.medical_specialty
Adolescent
Antipsychotic agents
Happiness
RC435-571
Logistic regression
Affect (psychology)
Correlation
03 medical and health sciences
0302 clinical medicine
030202 anesthesiology
Internal medicine
Brief Psychiatric Rating Scale
Medicine
Humans
Affective symptoms
Psychiatric Status Rating Scales
Psychiatry
Psychotic disorders
business.industry
medicine.disease
Thailand
030227 psychiatry
Psychiatry and Mental health
Cross-Sectional Studies
Schizophrenia
Well-being
Schizophrenic Psychology
business
Research Article
Subjects
Details
- Language :
- English
- Volume :
- 21
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Psychiatry
- Accession number :
- edsair.doi.dedup.....14191f6c16d04ba7698714ce171b2090