Santonin: a new method of extraction from, and quantitative determination inArtemisia caerulescens ssp.cretacea (fiori) br.-catt. & gubell. by high-performance liquid chromatography

Santonin, a sesquiterpene lactone characteristic of many species of the genus Artemisia, has hitherto been quantitatively determined by long and complicated gravimetric procedures. A new, rapid, simple and accurate extraction and analytical procedure has been established. This high-performance liquid chromatographic method employs a Licrospher 100-RP column and a mobile phase consisting of acetonitrile:water in a gradient programme. Copyright © 1998 John Wiley & Sons, Ltd.