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Elevated beta-thromboglobulin levels and circulating platelet aggregates in diabetic microangiopathy
- Source :
- Lancet (London, England). 1(8058)
- Publication Year :
- 1978
-
Abstract
- beta-Thromboglobulin levels and platelet-aggregate ratios were determined in blood-samples from healthy control subjects and from diabetic patients with and without microangiopathic complications. Patients with diabetic microangiopathy had significantly elevated beta-thromboglobulin levels and also reversible platelet aggregates. In nine newly treated diabetics blood-glucose control was associated with a significant fall in plasma beta-thromboglobulin. Since beta-thromboglobulin is a platelet-specific protein the results indicate that diabetic microangiopathy is associated with evidence of platelet activation and that this may be influenced by the degree of biochemical control.
- Subjects :
- Diabetic microangiopathy
Blood Platelets
medicine.medical_specialty
Diabetic Retinopathy
integumentary system
Platelet Aggregation
business.industry
Beta-Globulins
Thrombosis
General Medicine
Middle Aged
Capillaries
Endocrinology
Internal medicine
Healthy control
Diabetes Mellitus
Medicine
Humans
Platelet
Platelet activation
business
Diabetic Angiopathies
Aged
Subjects
Details
- ISSN :
- 01406736
- Volume :
- 1
- Issue :
- 8058
- Database :
- OpenAIRE
- Journal :
- Lancet (London, England)
- Accession number :
- edsair.doi.dedup.....13d500021d4f2d8016e646e305d84aa4