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Improvement in mood, oxidative stress, fatigue, and insomnia following supplementary management with RobuvitĀ®
- Source :
- Journal of neurosurgical sciences. 62(4)
- Publication Year :
- 2018
-
Abstract
- BACKGROUND Oxidative stress (OS) plays a substantial role in inflammatory and neurodegenerative diseases, causing cellular damage and mitochondrial dysfunction. OS also contributes to aging and severe neural disorders such as Alzheimer's and Parkinson's diseases. Previous registries have documented a reduction in OS levels with Robuvit® (Horphag Research, Ltd.), an extract from wood of the French oak (Quercus robur) that provides a decrease of OS as well as relief from chronic fatigue syndrome. The aim of the present registry was to investigate the influence of Robuvit® on a group of subjects presenting with mood disorders, oxidative stress, fatigue, and insomnia. METHODS Forty patients were recruited from a selection of patients with high OS levels as assessed with the d-ROMs test. Twenty-two subjects formed the control group following the standard management plan. The remaining 18 subjects formed the Robuvit® supplementation group. They received three capsules of Robuvit® 100 mg per day, for 8 weeks. RESULTS Tolerability to the supplementation with Robuvit® was overall good, and no safety concerns were raised. Mood tests showed a significant general improvement in 13 out of 16 items of the BMIS (P
- Subjects :
- Adult
Male
medicine.medical_specialty
030204 cardiovascular system & hematology
medicine.disease_cause
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Internal medicine
Sleep Initiation and Maintenance Disorders
Insomnia
medicine
Chronic fatigue syndrome
Humans
Fatigue
business.industry
Plant Extracts
Middle Aged
medicine.disease
Hydrolyzable Tannins
Clinical trial
Affect
Oxidative Stress
Mood
Tolerability
Mood disorders
Surgery
Female
Neurology (clinical)
Active treatment
medicine.symptom
business
030217 neurology & neurosurgery
Oxidative stress
Subjects
Details
- ISSN :
- 18271855
- Volume :
- 62
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of neurosurgical sciences
- Accession number :
- edsair.doi.dedup.....13d1414a337d4a5f7292ae8035726244