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Time to Onset of Paresthesia Among Community Members Exposed to the World Trade Center Disaster
- Source :
- International Journal of Environmental Research and Public Health, Vol 16, Iss 8, p 1429 (2019), International Journal of Environmental Research and Public Health, Volume 16, Issue 8
- Publication Year :
- 2019
- Publisher :
- MDPI AG, 2019.
-
Abstract
- We examined whether time to onset of paresthesia was associated with indicators of severity of World Trade Center (WTC) exposure. We analyzed data from 3411 patients from the Bellevue Hospital&mdash<br />WTC Environmental Health Center. Paresthesia was defined as present if the symptom occurred in the lower extremities with frequency &ldquo<br />often&rdquo<br />or &ldquo<br />almost continuous.&rdquo<br />We plotted hazard functions and used the log-rank test to compare time to onset of paresthesia between different exposure groups. We also used Cox regression analysis to examine risk factors for time-to-paresthesia after 9/11/2001 and calculate hazard ratios adjusted for potential confounders. We found significantly elevated hazard ratios for paresthesia for (a) working in a job that required cleaning of WTC dust in the workplace<br />and (b) being heavily exposed to WTC dust on September 11, 2001, after adjusting for age, race/ethnicity, depression, anxiety, post-traumatic stress disorder, and body mass index. These observational data are consistent with the hypothesis that exposure to WTC dust or some other aspect of cleaning WTC dust in the workplace, is associated with neuropathy and paresthesia. Further neurological evaluations of this and other WTC-exposed populations is warranted.
- Subjects :
- Adult
Male
Health, Toxicology and Mutagenesis
lcsh:Medicine
complex mixtures
Article
Disasters
paresthesia
03 medical and health sciences
0302 clinical medicine
Risk Factors
Humans
Medicine
030212 general & internal medicine
Depression (differential diagnoses)
Aged
Proportional Hazards Models
2. Zero hunger
business.industry
Proportional hazards model
neuropathic symptoms
Confounding
Hazard ratio
lcsh:R
Public Health, Environmental and Occupational Health
World trade center
Dust
Environmental Exposure
Middle Aged
030210 environmental & occupational health
humanities
3. Good health
Anxiety
Female
Observational study
September 11 Terrorist Attacks
medicine.symptom
business
Body mass index
World Trade Center exposure
Demography
Cox regression
hazard function
Subjects
Details
- Language :
- English
- ISSN :
- 16604601
- Volume :
- 16
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- International Journal of Environmental Research and Public Health
- Accession number :
- edsair.doi.dedup.....13aa46dfe6631784a36339c97271c842