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Amino-Terminal Pro-Brain Natriuretic Peptid in Prediction of Left Ventricular Ejection Fraction

Authors :
Mugdim Bajric
Nermin N. Salkic
Elnur Smajić
Jasmin Caluk
Ramiz Hajric
Elmir Jahic
Farid Ljuca
Denis Mrsic
Fahir Baraković
Zumreta Kusljugic
Mensura Ascerić
Source :
Bosnian Journal of Basic Medical Sciences, Vol 8, Iss 3 (2008)
Publication Year :
2008
Publisher :
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina, 2008.

Abstract

We aimed to evaluate levels of amino-terminal pro-brain natriuretic peptid (NT-proBNP) in prediction of left ventricular ejection fraction (LVEF) in heart failure patients. Prospective study on 60 consecutive patients with symptoms and signs of heart failure was performed. Blood samples for NT-proBNP analysis was taken from all test subjects and echocardiography was also done in all of them. According to LVEF value, patients were divided into four groups; those with 50%. NT-proBNP values correlated with LVEF value. Regression analyis was used to evaluate how well NT-proBNP values predict LVEF. We used Receiver Operating Characteristic Curve calculation to evaluate diagnostic performance of NT-proBNP in estimation of LVEF. Average value of NT-proBNP in test group was 3191,69±642,89 pg/ml (p

Details

Language :
English
ISSN :
18404812 and 15128601
Volume :
8
Issue :
3
Database :
OpenAIRE
Journal :
Bosnian Journal of Basic Medical Sciences
Accession number :
edsair.doi.dedup.....138ff2657d89fc43108cb4172a4cffaf