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Supplementary Methods, Figure Legends 1-7 from AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Authors :
Michelle D. Garrett
Neil T. Thompson
Paul Workman
Suzanne A. Eccles
Florence I. Raynaud
John F. Lyons
Thomas G. Davies
Steven J. Woodhead
Matthias Reule
Ruth E. Feltell
Paul S. Jones
Kathrin Heinzmann
Simon P. Heaton
Anna Zetterlund
Vanessa Martins
Alexis K. de Haven Brandon
Melanie R. Valenti
Paul D. Eve
Robert H. te Poele
Kyla M. Grimshaw
Mike I. Walton
Timothy A. Yap
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file - 81K, Supplementary data comprising the materials and methods for (i) crystallography (ii) gene expression studies (iii) siRNA studies and Supplementary Figure legends 1-7

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....136ef480c6dff64c10335140171ee9da
Full Text :
https://doi.org/10.1158/1078-0432.22446023.v1