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Automated retinal boundary segmentation of optical coherence tomography images using an improved Canny operator
- Source :
- Scientific Reports, Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Publishing Group UK, 2022.
-
Abstract
- Retinal segmentation is a prerequisite for quantifying retinal structural features and diagnosing related ophthalmic diseases. Canny operator is recognized as the best boundary detection operator so far, and is often used to obtain the initial boundary of the retina in retinal segmentation. However, the traditional Canny operator is susceptible to vascular shadows, vitreous artifacts, or noise interference in retinal segmentation, causing serious misdetection or missed detection. This paper proposed an improved Canny operator for automatic segmentation of retinal boundaries. The improved algorithm solves the problems of the traditional Canny operator by adding a multi-point boundary search step on the basis of the original method, and adjusts the convolution kernel. The algorithm was used to segment the retinal images of healthy subjects and age-related macular degeneration (AMD) patients; eleven retinal boundaries were identified and compared with the results of manual segmentation by the ophthalmologists. The average difference between the automatic and manual methods is: 2-6 microns (1~2 pixels) for healthy subjects and 3-10 microns (1~3 pixels) for AMD patients. Qualitative method is also used to verify the accuracy and stability of the algorithm. The percentage of “perfect segmentation” and “good segmentation” is 98% in healthy subjects and 94% in AMD patients. This algorithm can be used alone or in combination with other methods as an initial boundary detection algorithm. It is easy to understand and improve, and may become a useful tool for analyzing and diagnosing eye diseases.
- Subjects :
- genetic structures
Computer science
Science
Boundary (topology)
Article
Retina
chemistry.chemical_compound
Macular Degeneration
Optical coherence tomography
Image processing
medicine
Humans
Computer vision
Segmentation
Multidisciplinary
medicine.diagnostic_test
business.industry
Operator (physics)
Retinal
Middle Aged
eye diseases
chemistry
Medicine
Female
Artificial intelligence
business
Artifacts
Biomedical engineering
Algorithms
Tomography, Optical Coherence
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....136c0debc98013014861d77192060654