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Antinociception Induced by Verapamil and Chloramphenicol in Mice
- Source :
- Neonatology. 72:28-31
- Publication Year :
- 1997
- Publisher :
- S. Karger AG, 1997.
-
Abstract
- The analgesic effects of verapamil, a calcium channel blocker, and chloramphenicol, a phenicolated antibiotic, were compared using the test of acetic-acid-induced writhing and the hot-plate test in mice. The results suggest that both drugs have antinociceptive properties comparable to salicylate analgesia. No significant difference was found between verapamil- and chloramphenicol-induced analgesia (p < 0.05).
- Subjects :
- Male
medicine.drug_class
Analgesic
Antibiotics
Calcium channel blocker
Pharmacology
Mice
medicine
Animals
Hot plate test
Pain Measurement
Analgesics
Mice, Inbred BALB C
Behavior, Animal
business.industry
Chloramphenicol
Biological activity
Calcium Channel Blockers
Anti-Bacterial Agents
Nociception
Verapamil
Pediatrics, Perinatology and Child Health
Female
Analgesia
business
Developmental Biology
medicine.drug
Subjects
Details
- ISSN :
- 16617819 and 16617800
- Volume :
- 72
- Database :
- OpenAIRE
- Journal :
- Neonatology
- Accession number :
- edsair.doi.dedup.....132be2659347f0b9b6861ab45d79c4d5