Pseudoprogression during treatment with pembrolizumab followed by rechallenge with chemotherapy in metastatic colorectal cancer: A case report

Authors :: Torben Hansen
Natacha D. Trabjerg
Christina Rask
Lars Henrik Jensen
Source :: Clinical Case Reports, Vol 7, Iss 7, Pp 1445-1449 (2019), Trabjerg, N D, Rask, C, Jensen, L H & Hansen, T F 2019, ' Pseudoprogression during treatment with pembrolizumab followed by rechallenge with chemotherapy in metastatic colorectal cancer : A case report ', Clinical Case Reports, vol. 7, no. 7, pp. 1445-1449 . https://doi.org/10.1002/ccr3.2262, Clinical Case Reports
Publication Year :: 2019
Publisher :: Wiley, 2019.
Abstract: Disease progression during immunotherapy in colorectal cancer does not always indicate treatment failure. A case argues that carcinoembryonic antigen (CEA) may serve as an early marker to distinguish between pseudoprogression and real progression. Presentation of results from reintroduction of chemotherapy after progression on immunotherapy that suggest increased efficiency.

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