Efficacy of a single 6 mg/kg versus two 3 mg/kg caspofungin doses for treatment of disseminated candidiasis caused by Candida albicans in a neutropenic mouse model

We compared the efficacy of single six mg/kg and 2×3 mg/kg caspofungin doses to the traditional one mg/kg daily against C. albicans in a neutropenic murine model. in lethality experiments, all regimens improved survival (p