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Japonicins A and B from the flowers of Inula japonica
- Source :
- Journal of Asian Natural Products Research. 8:385-390
- Publication Year :
- 2006
- Publisher :
- Informa UK Limited, 2006.
-
Abstract
- Two new flavonols japonicins, A (1) and B (2), along with nine known flavonoids were isolated from an antidepressant fraction, which was separated from the 70% alcohol extract of the flowers of Inula japonica Thumb. The structures of compounds 1 and 2 were determined as 3,3',4',5,9,10-hexahydroxy-12-methylchroman[2,3-h]flavone and 8-(1-(3,4-dihydroxyphenyl)ethyl)-3,3',4',5,7-pentahydroxyflavone by the analyses of physical constants and spectral data. The special flavonoid structure having the substituent 1-phenylethyl at C-8 position was discovered for the first time.
- Subjects :
- Flavonoids
Pharmacology
chemistry.chemical_classification
Inula japonica
Magnetic Resonance Spectroscopy
Traditional medicine
Plant Extracts
Organic Chemistry
Flavonoid
Substituent
Pharmaceutical Science
Flowers
General Medicine
Antidepressive Agents
Analytical Chemistry
chemistry.chemical_compound
Flavonols
Complementary and alternative medicine
chemistry
Drug Discovery
Humans
Molecular Medicine
Inula
Spectral data
Phytotherapy
Subjects
Details
- ISSN :
- 14772213 and 10286020
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of Asian Natural Products Research
- Accession number :
- edsair.doi.dedup.....12d5ac0b2efb5c41e4c0d0ce437cd9c8