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Sequential ATRA/Reductive Cyclopropanation Reactions with a Ruthenium Catalyst in the Presence of Manganese
- Source :
- European Journal of Organic Chemistry. 2011:2272-2277
- Publication Year :
- 2011
- Publisher :
- Wiley, 2011.
-
Abstract
- Atom-transfer radical addition (ATRA) reactions of ethyl trichloroacetate, dichloromalononitrile, or diethyl 2,2-dichloromalonate with olefins followed by dechlorination have provided functionalized cyclopropanes in one step. The RuIII complex [Cp*RuCl2(PPh3)] was used as a catalyst precursor and commercial Mn powder as reducing agent. Reactions with the less activated substrate ethyl dichloroacetate gave ATRA products with high turnover numbers but cyclopropanation was not observed.
- Subjects :
- Organic-Synthesis
Controlled Polymerization
Cyclopropanation
Reducing agent
Donor-Acceptor Cyclopropanes
chemistry.chemical_element
Carbon-Carbon Bonds
Kharasch Addition
Tandem Catalysis
Medicinal chemistry
Ruthenium
Catalysis
chemistry.chemical_compound
Transfer Radical-Addition
Copper-Complexes
Organic chemistry
Kharasch addition
Physical and Theoretical Chemistry
Triphenylphosphine
Reduction
Manganese
Addition reaction
Reducing Agent
Radical reactions
Organic Chemistry
Free-radical reaction
chemistry
Cyclization Atrc Reactions
Subjects
Details
- ISSN :
- 1434193X
- Volume :
- 2011
- Database :
- OpenAIRE
- Journal :
- European Journal of Organic Chemistry
- Accession number :
- edsair.doi.dedup.....12c1ff95984f33ea23401d04b4070e79