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Biological interpretation of genome-wide association studies using predicted gene functions
Authors :
Pers TH Karjalainen JM Chan Y Westra HJ Wood AR Yang J Lui JC Vedantam S Gustafsson S Esko T Frayling T Speliotes EK Boehnke M Raychaudhuri S Fehrmann RS Hirschhorn JN Franke L Chu AY Estrada K Luan J Kutalik Z Amin N Buchkovich ML Croteau Chonka DC Day FR Duan Y Fall T Fehrmann R Ferreira T Jackson AU Karjalainen J Lo KS Locke AE Mägi R Mihailov E Porcu E Randall JC Scherag A Vinkhuyzen AA Winkler TW Workalemahu T Zhao JH Absher D Albrecht E Anderson D Baron J Beekman M Demirkan A Ehret GB Feenstra B Feitosa MF Fischer K Fraser RM Goel A Gong J Justice E Kanoni S Kleber ME Kristiansson K Lim U Lotay V Mangino M Mateo Leach I Medina Gomez C Nalls MA Nyholt DR Palmer CD Pasko D Pechlivanis S Prokopenko I Ried JS Ripke S Shungin D Stancáková A Strawbridge RJ Sung YJ Tanaka T Teumer A Trompet S van der Laan SW van Setten J Van Vliet Ostaptchouk JV Wang Z Yengo L Zhang W Afzal U Ärnlöv J Arscott GM Bandinelli S Barrett A Bellis C Bennett AJ Berne C Blüher M Bolton JL Böttcher Y Boyd HA Bruinenberg M Buckley BM Buyske S Caspersen IH Chines PS Clarke R Claudi Boehm S Cooper M Daw EW De Jong A Deelen J Delgado G Denny JC Dhonukshe Rutten R Dimitriou M Doney AS Dörr M Eklund N Eury E Folkersen L Garcia ME Geller F Giedraitis V Go AS Grallert H Grammer TB Gräßler J Grönberg H de Groot LC Groves CJ Haessler J Haller T Hallmans G Hannemann A Hartman CA Hassinen M Hayward C Heard Costa NL Helmer Q Hemani G Henders AK Hillege HL Hlatky MA Hoffmann W Hoffmann P Holmen O Houwing Duistermaat JJ Illig T Isaacs A James AL Jeff J Johansen B Johansson Å Jolley J Juliusdottir T Junttila J Kho AN Kinnunen L Klopp N Kocher T Kratzer W Lichtner P Lind L Lindström J Lobbens S Lorentzon M Lu Y Lyssenko V Magnusson PK Mahajan A Maillard M McArdle WL McKenzie CA McLachlan S McLaren PJ Menni C Merger S Milani L Moayyeri A Monda KL Morken MA Müller G Müller Nurasyid M Musk AW Narisu N Nauck M Nolte IM Nöthen MM Oozageer L Pilz S Rayner NW Renstrom F Robertson NR Rose LM Roussel R Sanna S Scharnagl H Scholtens S Schumacher FR Schunkert H Scott RA Sehmi J Seufferlein T Shi J Silventoinen K Smit JH Smith AV Smolonska J Stanton AV Stirrups K Stott DJ Stringham HM Sundström J Swertz MA Syvänen AC Tayo BO Thorleifsson G Tyrer JP van Dijk S van Schoor NM van der Velde N van Heemst D van Oort FV Vermeulen SH Verweij N Vonk JM Waite LL Waldenberger M Wennauer R Wilkens LR Willenborg C Wilsgaard T Wojczynski MK Wong A Wright AF Zhang Q Arveiler D Bakker SJ Beilby J Bergman RN Bergmann S Biffar R Blangero J Boomsma I Bornstein SR Bovet P BRAMBILLA, PAOLO Brown MJ Campbell H Caulfield MJ Chakravarti A Collins R Collins FS Crawford DC Cupples LA Danesh J de Faire U den Ruijter HM Erbel R Erdmann J Eriksson JG Farrall M Ferrannini E Ferrières J Ford I Forouhi NG Forrester T Gansevoort RT Gejman PV Gieger C Golay A Gottesman O Gudnason V Gyllensten U Haas DW Hall AS Harris TB Hattersley AT Heath AC Hengstenberg C Hicks AA Hindorff LA Hingorani AD Hofman A Hovingh GK Humphries SE Hunt SC Hypponen E Jacobs KB Jarvelin MR Jousilahti P Jula AM Kaprio J Kastelein JJ Kayser M Kee F Keinanen Kiukaanniemi SM Kiemeney LA Kooner JS Kooperberg C Koskinen S Kovacs P Kraja AT Kumari M Kuusisto J Lakka TA Langenberg C Le Marchand L Lehtimäki T Lupoli S Madden PA Männistö S Manunta P Marette A Matise TC McKnight B Meitinger T Moll FL Montgomery GW Morris AD Morris AP Murray JC Nelis M Ohlsson C Oldehinkel AJ Ong KK Ouwehand WH Pasterkamp G Peters A Pramstaller PP Price JF Qi L Raitakari OT Rankinen T Rao DC Rice TK Ritchie M Rudan I Salomaa V Samani NJ Saramies J Sarzynski MA Schwarz PE Sebert S Sever P Shuldiner AR Sinisalo J Steinthorsdottir V Stolk RP Tardif JC Tönjes A Tremblay A Tremoli E Virtamo J Vohl MC Amouyel P Asselbergs FW Assimes TL Bochud M Boehm BO Boerwinkle E Bottinger EP Bouchard C Cauchi S Chambers JC Chanock SJ Cooper RS de Bakker PI Dedoussis G Ferrucci L Franks PW Froguel P Groop LC Haiman CA Hamsten A Hayes MG Hui J Hunter DJ Hveem K Jukema JW Kaplan RC Kivimaki M Kuh D Laakso M Liu Y Martin NG März W Melbye M Moebus S Munroe PB Njølstad I Oostra BA Palmer CN Pedersen NL Perola M Pérusse L Peters U Powell JE Power C Quertermous T Rauramaa R Reinmaa E Ridker PM Rivadeneira F Rotter JI Saaristo TE Saleheen D Schlessinger D Slagboom PE Snieder H Spector TD Strauch K Stumvoll M Tuomilehto J Uusitupa M van der Harst P Völzke H Walker M Wareham NJ Watkins H Wichmann HE Wilson JF Zanen P Deloukas P Heid IM Lindgren CM Mohlke KL Thorsteinsdottir U Barroso I Fox CS North KE Strachan DP Beckmann JS Berndt SI Borecki IB McCarthy MI Metspalu A Stefansson K Uitterlinden AG van Duijn CM Willer CJ Price AL Lettre G Loos RJ Weedon MN Ingelsson E O'Connell JR Abecasis GR Chasman DI Goddard ME Visscher PM Frayling T.M. Damage and Repair in Cancer Development and Cancer Treatment (DARE) Guided Treatment in Optimal Selected Cancer Patients (GUTS) Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI) Stem Cell Aging Leukemia and Lymphoma (SALL) Genetic Investigation of ANthropometric Traits (GIANT) Consortium Wood, AR. Esko, T. Yang, J. Vedantam, S. Pers, TH. Gustafsson, S. Chu, AY. Estrada, K. Luan£££Jian'an£££ J. Kutalik£££Zoltán£££ Z. Amin, N. Buchkovich, ML. Croteau-Chonka, DC. Day, FR. Duan, Y. Fall, T. Fehrmann, R. Ferreira, T. Jackson, AU. Karjalainen, J. Lo, KS. Locke, AE. Mägi, R. Mihailov, E. Porcu, E. Randall, JC. Scherag, A. Vinkhuyzen, AA. Westra, HJ. Winkler, TW. Workalemahu, T. Zhao, JH. Absher, D. Albrecht, E. Anderson, D. Baron, J. Beekman, M. Demirkan, A. Ehret, GB. Feenstra, B. Feitosa, MF. Fischer, K. Fraser, RM. Goel, A. Gong, J. Justice, E. Kanoni, S. Kleber, ME. Kristiansson, K. Lim, U. Lotay, V. Lui, JC. Mangino, M. Mateo Leach, I. Medina-Gomez, C. Nalls, MA. Nyholt, DR. Palmer, CD. Pasko, D. Pechlivanis, S. Prokopenko, I. Ried, JS. Ripke, S. Shungin, D. Stancáková, A. Strawbridge, RJ. Sung, YJ. Tanaka, T. Teumer, A. Trompet, S. van der Laan SW. van Setten, J. Van Vliet-Ostaptchouk JV. Wang, Z. Yengo£££Loïc£££ L. Zhang, W. Afzal, U. Ärnlöv, J. Arscott, GM. Bandinelli, S. Barrett, A. Bellis, C. Bennett, AJ. Berne, C. Blüher, M. Bolton, JL. Böttcher, Y. Boyd, HA. Bruinenberg, M. Buckley, BM. Buyske, S. Caspersen, IH. Chines, PS. Clarke, R. Claudi-Boehm, S. Cooper, M. Daw, EW. De Jong, A. Deelen, J. Delgado, G. Denny, JC. Dhonukshe-Rutten, R. Dimitriou, M. Doney, AS. Dörr, M. Eklund, N. Eury, E. Folkersen, L. Garcia, ME. Geller, F. Giedraitis, V. Go, AS. Grallert, H. Grammer, TB. Gräßler, J. Grönberg, H. de Groot LC. Groves, CJ. Haessler, J. Haller, T. Hallmans, G. Hannemann, A. Hartman, CA. Hassinen, M. Hayward, C. Heard-Costa, NL. Helmer, Q. Hemani, G. Henders, AK. Hillege, HL. Hlatky, MA. Hoffmann, W. Hoffmann, P. Holmen, O. Houwing-Duistermaat, JJ. Illig, T. Isaacs, A. James, AL. Jeff, J. Johansen, B. Johansson£££Åsa£££ Å. Jolley, J. Juliusdottir, T. Junttila, J. Kho, AN. Kinnunen, L. Klopp, N. Kocher, T. Kratzer, W. Lichtner, P. Lind, L. Lindström, J. Lobbens, S. Lorentzon, M. Lu, Y. Lyssenko, V. Magnusson, PK. Mahajan, A. Maillard, M. McArdle, WL. McKenzie, CA. McLachlan, S. McLaren, PJ. Menni, C. Merger, S. Milani, L. Moayyeri, A. Monda, KL. Morken, MA. Müller, G. Müller-Nurasyid, M. Musk, AW. Narisu, N. Nauck, M. Nolte, IM. Nöthen, MM. Oozageer, L. Pilz, S. Rayner, NW. Renstrom, F. Robertson, NR. Rose, LM. Roussel, R. Sanna, S. Scharnagl, H. Scholtens, S. Schumacher, FR. Schunkert, H. Scott, RA. Sehmi, J. Seufferlein, T. Shi, J. Silventoinen, K. Smit, JH. Smith, AV. Smolonska, J. Stanton, AV. Stirrups, K. Stott, DJ. Stringham, HM. Sundström, J. Swertz, MA. Syvänen, AC. Tayo, BO. Thorleifsson, G. Tyrer, JP. van Dijk, S. van Schoor NM. van der Velde, N. van Heemst, D. van Oort FV. Vermeulen, SH. Verweij, N. Vonk, JM. Waite, LL. Waldenberger, M. Wennauer, R. Wilkens, LR. Willenborg, C. Wilsgaard, T. Wojczynski, MK. Wong, A. Wright, AF. Zhang, Q. Arveiler, D. Bakker, SJ. Beilby, J. Bergman, RN. Bergmann, S. Biffar, R. Blangero, J. Boomsma, I. Bornstein, SR. Bovet, P. Brambilla, P. Brown, MJ. Campbell, H. Caulfield, MJ. Chakravarti, A. Collins, R. Collins, FS. Crawford, DC. Cupples, LA. Danesh, J. de Faire, U. den Ruijter HM. Erbel, R. Erdmann, J. Eriksson, JG. Farrall, M. Ferrannini, E. Ferrières, J. Ford, I. Forouhi, NG. Forrester, T. Gansevoort, RT. Gejman, PV. Gieger, C. Golay, A. Gottesman, O. Gudnason, V. Gyllensten, U. Haas, DW. Hall, AS. Harris, TB. Hattersley, AT. Heath, AC. Hengstenberg, C. Hicks, AA. Hindorff, LA. Hingorani, AD. Hofman, A. Hovingh, GK. Humphries, SE. Hunt, SC. Hypponen, E. Jacobs, KB. Jarvelin, MR. Jousilahti, P. Jula, AM. Kaprio, J. Kastelein, JJ. Kayser, M. Kee, F. Keinanen-Kiukaanniemi, SM. Kiemeney, LA. Kooner, JS. Kooperberg, C. Koskinen, S. Kovacs, P. Kraja, AT. Kumari, M. Kuusisto, J. Lakka, TA. Langenberg, C. Le Marchand, L. Lehtimäki, T. Lupoli, S. Madden, PA. Männistö, S. Manunta, P. Marette, A. Matise, TC. McKnight, B. Meitinger, T. Moll, FL. Montgomery, GW. Morris, AD. Morris, AP. Murray, JC. Nelis, M. Ohlsson, C. Oldehinkel, AJ. Ong, KK. Ouwehand, WH. Pasterkamp, G. Peters, A. Pramstaller, PP. Price, JF. Qi, L. Raitakari, OT. Rankinen, T. Rao, DC. Rice, TK. Ritchie, M. Rudan, I. Salomaa, V. Samani, NJ. Saramies, J. Sarzynski, MA. Schwarz, PE. Sebert, S. Sever, P. Shuldiner, AR. Sinisalo, J. Steinthorsdottir, V. Stolk, RP. Tardif, JC. Tönjes, A. Tremblay, A. Tremoli, E. Virtamo, J. Vohl, MC. Amouyel, P. Asselbergs, FW. Assimes, TL. Bochud, M. Boehm, BO. Boerwinkle, E. Bottinger, EP. Bouchard, C. Cauchi, S. Chambers, JC. Chanock, SJ. Cooper, RS. de Bakker PI. Dedoussis, G. Ferrucci, L. Franks, PW. Froguel, P. Groop, LC. Haiman, CA. Hamsten, A. Hayes, MG. Hui, J. Hunter, DJ. Hveem, K. Jukema, JW. Kaplan, RC. Kivimaki, M. Kuh, D. Laakso, M. Liu, Y. Martin, NG. März, W. Melbye, M. Moebus, S. Munroe, PB. Njølstad, I. Oostra, BA. Palmer, CN. Pedersen, NL. Perola, M. Pérusse, L. Peters, U. Powell, JE. Power, C. Quertermous, T. Rauramaa, R. Reinmaa, E. Ridker, PM. Rivadeneira, F. Rotter, JI. Saaristo, TE. Saleheen, D. Schlessinger, D. Slagboom, PE. Snieder, H. Spector, TD. Strauch, K. Stumvoll, M. Tuomilehto, J. Uusitupa, M. van der Harst, P. Völzke, H. Walker, M. Wareham, NJ. Watkins, H. Wichmann, HE. Wilson, JF. Zanen, P. Deloukas, P. Heid, IM. Lindgren, CM. Mohlke, KL. Speliotes, EK. Thorsteinsdottir, U. Barroso£££Inês£££ I. Fox, CS. North, KE. Strachan, DP. Beckmann, JS. Berndt, SI. Boehnke, M. Borecki, IB. McCarthy, MI. Metspalu, A. Stefansson, K. Uitterlinden, AG. van Duijn CM. Franke, L. Willer, CJ. Price, AL. Lettre, G. Loos, RJ. Weedon, MN. Ingelsson, E. O'Connell, JR. Abecasis, GR. Chasman, DI. Goddard, ME. Visscher, PM. Hirschhorn, JN. Frayling, TM. Clinicum Jaakko Kaprio / Principal Investigator Department of Public Health Institute for Molecular Medicine Finland Genetic Epidemiology Pers, T Karjalainen, J Chan, Y Westra, H Wood, A Yang, J Lui, J Vedantam, S Gustafsson, S Esko, T Frayling, T Speliotes, E Boehnke, M Raychaudhuri, S Fehrmann, R Hirschhorn, J Franke, L Chu, A Estrada, K Luan, J Kutalik, Z Amin, N Buchkovich, M Croteau Chonka, D Day, F Duan, Y Fall, T Ferreira, T Jackson, A Lo, K Locke, A Mägi, R Mihailov, E Porcu, E Randall, J Scherag, A Vinkhuyzen, A Winkler, T Workalemahu, T Zhao, J Absher, D Albrecht, E Anderson, D Baron, J Beekman, M Demirkan, A Ehret, G Feenstra, B Feitosa, M Fischer, K Fraser, R Goel, A Gong, J Justice, E Kanoni, S Kleber, M Kristiansson, K Lim, U Lotay, V Mangino, M Mateo Leach, I Medina Gomez, C Nalls, M Nyholt, D Palmer, C Pasko, D Pechlivanis, S Prokopenko, I Ried, J Ripke, S Shungin, D Stancáková, A Strawbridge, R Sung, Y Tanaka, T Teumer, A Trompet, S van der Laan, S van Setten, J Van Vliet Ostaptchouk, J Wang, Z Yengo, L Zhang, W Afzal, U Ärnlöv, J Arscott, G Bandinelli, S Barrett, A Bellis, C Bennett, A Berne, C Blüher, M Bolton, J Böttcher, Y Boyd, H Bruinenberg, M Buckley, B Buyske, S Caspersen, I Chines, P Clarke, R Claudi Boehm, S Cooper, M Daw, E De Jong, A Deelen, J Delgado, G Denny, J Dhonukshe Rutten, R Dimitriou, M Doney, A Dörr, M Eklund, N Eury, E Folkersen, L Garcia, M Geller, F Giedraitis, V Go, A Grallert, H Grammer, T Gräßler, J Grönberg, H de Groot, L Groves, C Haessler, J Haller, T Hallmans, G Hannemann, A Hartman, C Hassinen, M Hayward, C Heard Costa, N Helmer, Q Hemani, G Henders, A Hillege, H Hlatky, M Hoffmann, W Hoffmann, P Holmen, O Houwing Duistermaat, J Illig, T Isaacs, A James, A Jeff, J Johansen, B Johansson, Å Jolley, J Juliusdottir, T Junttila, J Kho, A Kinnunen, L Klopp, N Kocher, T Kratzer, W Lichtner, P Lind, L Lindström, J Lobbens, S Lorentzon, M Lu, Y Lyssenko, V Magnusson, P Mahajan, A Maillard, M Mcardle, W Mckenzie, C Mclachlan, S Mclaren, P Menni, C Merger, S Milani, L Moayyeri, A Monda, K Morken, M Müller, G Müller Nurasyid, M Musk, A Narisu, N Nauck, M Nolte, I Nöthen, M Oozageer, L Pilz, S Rayner, N Renstrom, F Robertson, N Rose, L Roussel, R Sanna, S Scharnagl, H Scholtens, S Schumacher, F Schunkert, H Scott, R Sehmi, J Seufferlein, T Shi, J Silventoinen, K Smit, J Smith, A Smolonska, J Stanton, A Stirrups, K Stott, D Stringham, H Sundström, J Swertz, M Syvänen, A Tayo, B Thorleifsson, G Tyrer, J van Dijk, S van Schoor, N van der Velde, N van Heemst, D van Oort, F Vermeulen, S Verweij, N Vonk, J Waite, L Waldenberger, M Wennauer, R Wilkens, L Willenborg, C Wilsgaard, T Wojczynski, M Wong, A Wright, A Zhang, Q Arveiler, D Bakker, S Beilby, J Bergman, R Bergmann, S Biffar, R Blangero, J Boomsma, I Bornstein, S Bovet, P Brambilla, P Brown, M Campbell, H Caulfield, M Chakravarti, A Collins, R Collins, F Crawford, D Cupples, L Danesh, J de Faire, U den Ruijter, H Erbel, R Erdmann, J Eriksson, J Farrall, M Ferrannini, E Ferrières, J Ford, I Forouhi, N Forrester, T Gansevoort, R Gejman, P Gieger, C Golay, A Gottesman, O Gudnason, V Gyllensten, U Haas, D Hall, A Harris, T Hattersley, A Heath, A Hengstenberg, C Hicks, A Hindorff, L Hingorani, A Hofman, A Hovingh, G Humphries, S Hunt, S Hypponen, E Jacobs, K Jarvelin, M Jousilahti, P Jula, A Kaprio, J Kastelein, J Kayser, M Kee, F Keinanen Kiukaanniemi, S Kiemeney, L Kooner, J Kooperberg, C Koskinen, S Kovacs, P Kraja, A Kumari, M Kuusisto, J Lakka, T Langenberg, C Le Marchand, L Lehtimäki, T Lupoli, S Madden, P Männistö, S Manunta, P Marette, A Matise, T Mcknight, B Meitinger, T Moll, F Montgomery, G Morris, A Murray, J Nelis, M Ohlsson, C Oldehinkel, A Ong, K Ouwehand, W Pasterkamp, G Peters, A Pramstaller, P Price, J Qi, L Raitakari, O Rankinen, T Rao, D Rice, T Ritchie, M Rudan, I Salomaa, V Samani, N Saramies, J Sarzynski, M Schwarz, P Sebert, S Sever, P Shuldiner, A Sinisalo, J Steinthorsdottir, V Stolk, R Tardif, J Tönjes, A Tremblay, A Tremoli, E Virtamo, J Vohl, M Amouyel, P Asselbergs, F Assimes, T Bochud, M Boehm, B Boerwinkle, E Bottinger, E Bouchard, C Cauchi, S Chambers, J Chanock, S Cooper, R de Bakker, P Dedoussis, G Ferrucci, L Franks, P Froguel, P Groop, L Haiman, C Hamsten, A Hayes, M Hui, J Hunter, D Hveem, K Jukema, J Kaplan, R Kivimaki, M Kuh, D Laakso, M Liu, Y Martin, N März, W Melbye, M Moebus, S Munroe, P Njølstad, I Oostra, B Pedersen, N Perola, M Pérusse, L Peters, U Powell, J Power, C Quertermous, T Rauramaa, R Reinmaa, E Ridker, P Rivadeneira, F Rotter, J Saaristo, T Saleheen, D Schlessinger, D Slagboom, P Snieder, H Spector, T Strauch, K Stumvoll, M Tuomilehto, J Uusitupa, M van der Harst, P Völzke, H Walker, M Wareham, N Watkins, H Wichmann, H Wilson, J Zanen, P Deloukas, P Heid, I Lindgren, C Mohlke, K Thorsteinsdottir, U Barroso, I Fox, C North, K Strachan, D Beckmann, J Berndt, S Borecki, I Mccarthy, M Metspalu, A Stefansson, K Uitterlinden, A van Duijn, C Willer, C Price, A Lettre, G Loos, R Weedon, M Ingelsson, E O'Connell, J Abecasis, G Chasman, D Goddard, M Visscher, P APH - Amsterdam Public Health AMS - Amsterdam Movement Sciences Geriatrics Other departments ACS - Amsterdam Cardiovascular Sciences Vascular Medicine Pers, Th Karjalainen, Jm Westra, Hj Wood, Ar Lui, Jc Speliotes, Ek Hirschhorn, Jn Faculty of Health Sciences
Source :
Nature Communications, 6:5890. Nature Publishing Group, Europe PubMed Central, Nature Communications, vol. 6, pp. 5890, Nature Communications, 6, 5890, Nature Communications, Nature Communications [E], 6, 5890. Nature Publishing Group, Pers, T H, Karjalainen, J M, Chan, Y, Westra, H-J, Wood, A R, Yang, J, Lui, J C, Vedantam, S, Gustafsson, S, Esko, T, Frayling, T, Speliotes, E K, Boehnke, M, Raychaudhuri, S, Fehrmann, R S N, Hirschhorn, J N, Franke, L, McLachlan, S, Campbell, H, Price, J & Rudan, I & Wilson, J 2015, ' Biological interpretation of genome-wide association studies using predicted gene functions ', Nature Communications, vol. 6, 5890 . https://doi.org/10.1038/ncomms6890, Nature Communications, 6, pp. 5890, Nature communications, 6. Nature Publishing Group
Publication Year :
2015
Abstract
Article<br />The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present DEPICT, an integrative tool that employs predicted gene functions to systematically prioritize the most likely causal genes at associated loci, highlight enriched pathways and identify tissues/cell types where genes from associated loci are highly expressed. DEPICT is not limited to genes with established functions and prioritizes relevant gene sets for many phenotypes.<br />published version<br />http://purl.org/eprint/status/PeerReviewed
Details
Language :
English
ISSN :
20411723
Database :
OpenAIRE
Journal :
Nature Communications, 6:5890. Nature Publishing Group, Europe PubMed Central, Nature Communications, vol. 6, pp. 5890, Nature Communications, 6, 5890, Nature Communications, Nature Communications [E], 6, 5890. Nature Publishing Group, Pers, T H, Karjalainen, J M, Chan, Y, Westra, H-J, Wood, A R, Yang, J, Lui, J C, Vedantam, S, Gustafsson, S, Esko, T, Frayling, T, Speliotes, E K, Boehnke, M, Raychaudhuri, S, Fehrmann, R S N, Hirschhorn, J N, Franke, L, McLachlan, S, Campbell, H, Price, J & Rudan, I & Wilson, J 2015, ' Biological interpretation of genome-wide association studies using predicted gene functions ', Nature Communications, vol. 6, 5890 . https://doi.org/10.1038/ncomms6890, Nature Communications, 6, pp. 5890, Nature communications, 6. Nature Publishing Group
Accession number :
edsair.doi.dedup.....12c01dc19a09cb0c6a0e1b23d60806ae
Full Text :
https://doi.org/10.1038/ncomms6890