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The physiological effects of creatine supplementation in fetal sheep before, during, and after umbilical cord occlusion and global hypoxia
- Source :
- Journal of Applied Physiology. 131:1088-1099
- Publication Year :
- 2021
- Publisher :
- American Physiological Society, 2021.
-
Abstract
- Direct fetal creatine supplementation increased plasma and cerebral creatine concentrations but did not alter fetal body weight, basal cardiovascular output, or blood chemistry. Creatine-treated fetuses displayed changes to arterial oxygenation 24–72 h after acute global hypoxia. An increase in striatum total creatine levels following UCO was also noted and suggests that increasing creatine tissue availability may be an adaptive response against the effects of hypoxia.
- Subjects :
- medicine.medical_specialty
Physiology
Creatine
Umbilical Cord
chemistry.chemical_compound
Basal (phylogenetics)
Fetus
Pregnancy
Physiology (medical)
Internal medicine
medicine
Animals
Umbilical Cord Occlusion
Hypoxia
Sheep
business.industry
Fetal Body Weight
Hypoxia (medical)
Fetal physiology
Endocrinology
chemistry
Blood chemistry
Dietary Supplements
Female
medicine.symptom
business
Subjects
Details
- ISSN :
- 15221601 and 87507587
- Volume :
- 131
- Database :
- OpenAIRE
- Journal :
- Journal of Applied Physiology
- Accession number :
- edsair.doi.dedup.....12b81e753d8489d48ef636285c98078b