Synthesis of amphiphilic galactopyranosyl diamines and amino alcohols as antitubercular agents

Mono- and diacylated derivatives of galactopyranosyl amines were obtained from d -galactose, via aminated intermediates prepared by reaction of 6-deoxy-6-iodo-1,2:3,4-di- O -isopropylidene-α- d -galactopyranose with 1,3-propanediamine, 1,2-ethanediamine or ethanolamine. Monoacylated derivatives displayed antitubercular activity.