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Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della societa italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design
- Publication Year :
- 2018
-
Abstract
- Background: Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%–2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable clinical presentations, including aneurysmal dilation of the aortic root and/or ascending thoracic aorta, isthmic coarctation, aortic dissection, or wall rupture. Methods: The REgistro della Valvola Aortica Bicuspide della Societa Italiana di ECocardiografia e CArdiovascular Imaging is a retrospective (from January 1, 2010)/prospective, multicenter, observational registry, expected to enroll 3000 patients with definitive diagnosis of BAV made by transthoracic and/or transesophageal echocardiography, computed tomography, cardiovascular magnetic resonance, or at surgery. Inclusion criteria were definitive diagnosis of BAV. Patients will be enrolled regardless of the presence and severity of aortic valve dysfunction or aortic vessel disease and the coexistence of other congenital cardiovascular malformations. Exclusion criteria were uncertain BAV diagnosis, impossibility of obtaining informed consent, inability to carry out the follow-up. Anamnestic, demographic, clinical, and instrumental data collected both at first evaluation and during follow-up will be integrated into dedicated software. The aim is to derive a data set of unselected BAV patients with the main purpose of assessing the current clinical presentation, management, and outcomes of BAV. Conclusions: A multicenter registry covering a large population of BAV patients could have a profound impact on the understanding of the natural history of this disease and could influence its management.
- Subjects :
- Aortic valve
medicine.medical_specialty
bicuspid aortic valve
Heart disease
Population
aortopathy
030204 cardiovascular system & hematology
03 medical and health sciences
cardiovascular magnetic resonance
Aortic dilation
ascending thoracic aorta
computed tomography
echocardiography
Radiology, Nuclear Medicine and Imaging
Cardiology and Cardiovascular Medicine
0302 clinical medicine
Bicuspid aortic valve
Internal medicine
medicine.artery
Nuclear Medicine and Imaging
medicine
Endocarditis
Thoracic aorta
Radiology, Nuclear Medicine and imaging
030212 general & internal medicine
education
Aortic dissection
education.field_of_study
business.industry
medicine.disease
Stenosis
medicine.anatomical_structure
cardiovascular system
Cardiology
business
Radiology
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....122b67137783989f8d697af508999e37